SCOPe 2.08: Domain d4jr2b1: 4jr2 B:57-302

Lineage for d4jr2b1 (4jr2 B:57-302)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-7 [63961] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63962] (12 PDB entries)
   Uniprot P55210 57-303

8. Domain d4jr2b1: 4jr2 B:57-302 [193129]
   Other proteins in same PDB: d4jr2a2, d4jr2b2
   automated match to d1i4oa_
   complexed with cl

Details for d4jr2b1

PDB Entry: 4jr2, 1.65 Å

PDB Description: human procaspase-7/caspase-7 heterodimer bound to ac-devd-cmk

PDB Compounds: (B:) procaspase-7

SCOPe Domain Sequences for d4jr2b1:

Sequence, based on SEQRES records:

>d4jr2b1 c.17.1.1 (B:57-302) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktlle
kpklffiqacrgtelddgiqaasgpindtdanprykipveadflfaystvpgyyswrspg
rgswfvqalcsileehgkdleimqiltrvndrvarhfesqsddphfhekkqipcvvsmlt
kelyfs

Sequence, based on observed residues (ATOM records):

>d4jr2b1 c.17.1.1 (B:57-302) Caspase-7 {Human (Homo sapiens) [TaxId: 9606]}
tyqynmnfeklgkciiinnknfdkvtgmgvrngtdkdaealfkcfrslgfdvivyndcsc
akmqdllkkaseedhtnaacfacillshgeenviygkdgvtpikdltahfrgdrcktlle
kpklffiqacrgtelddgiqakipveadflfaystvpgyyswrspgrgswfvqalcsile
ehgkdleimqiltrvndrvarhfesqsddphfhekkqipcvvsmltkelyfs

Timeline for d4jr2b1:

• d4jr2b1 first appeared in SCOPe 2.02, called d4jr2b_
  
• d4jr2b1 appears in SCOPe 2.07