SCOPe 2.06: Domain d4jqzb1: 4jqz B:34-277

Lineage for d4jqzb1 (4jqz B:34-277)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (28 PDB entries)

8. Domain d4jqzb1: 4jqz B:34-277 [193122]
   Other proteins in same PDB: d4jqza2, d4jqzb2
   automated match to d2j30a_

Details for d4jqzb1

PDB Entry: 4jqz, 2.89 Å

PDB Description: human procaspase-3, crystal form 2

PDB Compounds: (B:) Procaspase-3

SCOPe Domain Sequences for d4jqzb1:

Sequence, based on SEQRES records:

>d4jqzb1 c.17.1.1 (B:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqaargteldcgietdsgvdddmachkipveadflyaystapgyyswrnskdgs
wfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkel
yfyh

Sequence, based on observed residues (ATOM records):

>d4jqzb1 c.17.1.1 (B:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnkntdvdaanlretfrnlkyevrnkndltreeivelmrdvsk
edhskrssfvcvllsifgtngpvdlkkitnffrgdrcrsltgkpklfiiqahkipveadf
lyaystgswfiqslcamlkqyadklefmhiltrvnrkvatefesqipcivsmltkelyfy
h

Timeline for d4jqzb1:

• d4jqzb1 first appeared in SCOPe 2.02, called d4jqzb_
  
• d4jqzb1 was called d4jqzb_ in SCOPe 2.05
  
• d4jqzb1 appears in SCOPe 2.07
  
• d4jqzb1 appears in the current release, SCOPe 2.08