SCOPe 2.01: Domain d1erra_: 1err A:

Lineage for d1erra_ (1err A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (57 PDB entries)
   Uniprot P03372 307-551

8. Domain d1erra_: 1err A: [19298]
   complexed with ral

Details for d1erra_

PDB Entry: 1err, 2.6 Å

PDB Description: human estrogen receptor ligand-binding domain in complex with raloxifene

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d1erra_:

Sequence, based on SEQRES records:

>d1erra_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemlda
h

Sequence, based on observed residues (ATOM records):

>d1erra_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvyeekdhihrvldkitdtlihlmakaglt
lqqqhqrlaqlllilshirhmsnkgmehlysmplydlllemldah

Timeline for d1erra_:

• d1erra_ first appeared (with stable ids) in SCOP 1.55
  
• d1erra_ appears in SCOP 1.75
  
• d1erra_ appears in SCOPe 2.02
  
• d1erra_ appears in the current release, SCOPe 2.08