SCOPe 2.08: Domain d1a52a_: 1a52 A:

Lineage for d1a52a_ (1a52 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d1a52a_: 1a52 A: [19296]
   complexed with au, est

Details for d1a52a_

PDB Entry: 1a52, 2.8 Å

PDB Description: estrogen receptor alpha ligand-binding domain complexed to estradiol

PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d1a52a_:

Sequence; same for both SEQRES and ATOM records:

>d1a52a_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqherlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

Timeline for d1a52a_:

• d1a52a_ first appeared (with stable ids) in SCOP 1.55
  
• d1a52a_ appears in SCOPe 2.07