SCOP 1.71: Domain d1qkta_: 1qkt A:

Lineage for d1qkta_ (1qkt A:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (19 PDB entries)

8. Domain d1qkta_: 1qkt A: [19295]
   complex with estradiol
   complexed with est; mutant

Details for d1qkta_

PDB Entry: 1qkt, 2.2 Å

PDB Description: mutant estrogen nuclear receptor ligand binding domain complexed with estradiol

SCOP Domain Sequences for d1qkta_:

Sequence; same for both SEQRES and ATOM records:

>d1qkta_ a.123.1.1 (A:) Estrogen receptor alpha {Human (Homo sapiens)}
nslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakr
vpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmve
ifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkit
dtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllem
ldahrlha

Timeline for d1qkta_:

• d1qkta_ first appeared (with stable ids) in SCOP 1.55
  
• d1qkta_ appears in SCOP 1.69
  
• d1qkta_ appears in SCOP 1.73
  
• d1qkta_ appears in the current release, SCOPe 2.08