SCOPe 2.05: Domain d4h84a_: 4h84 A:

Lineage for d4h84a_ (4h84 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein automated matches [190182] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186920] (32 PDB entries)

8. Domain d4h84a_: 4h84 A: [192944]
   automated match to d1os9a_
   complexed with ca, gol, peg, pgo, pgr, y38, zn

Details for d4h84a_

PDB Entry: 4h84, 1.59 Å

PDB Description: crystal structure of the catalytic domain of human mmp12 in complex with a selective carboxylate based inhibitor.

PDB Compounds: (A:) Macrophage metalloelastase

SCOPe Domain Sequences for d4h84a_:

Sequence; same for both SEQRES and ATOM records:

>d4h84a_ d.92.1.11 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvfa
rgahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighsl
glghssdpkavmfptykyvdintfrlsaddirgiqslyg

Timeline for d4h84a_:

• d4h84a_ first appeared in SCOPe 2.02
  
• d4h84a_ appears in SCOPe 2.04
  
• d4h84a_ is called d4h84a1 in SCOPe 2.06
  
• d4h84a_ appears in the current release, SCOPe 2.08, called d4h84a1