SCOPe 2.08: Domain d4elbb1: 4elb B:1-162

Lineage for d4elbb1 (4elb B:1-162)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.0: automated matches [191485] (1 protein)
   not a true family

6. Protein automated matches [190777] (28 species)
   not a true protein

7. Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [188674] (20 PDB entries)

8. Domain d4elbb1: 4elb B:1-162 [192884]
   Other proteins in same PDB: d4elba2, d4elbb2, d4elbc2, d4elbd2, d4elbe2, d4elbf2, d4elbg2, d4elbh2
   automated match to d3fl8a_
   complexed with 34r, 34s, ca, cl

Details for d4elbb1

PDB Entry: 4elb, 2.6 Å

PDB Description: Structure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductase

PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d4elbb1:

Sequence; same for both SEQRES and ATOM records:

>d4elbb1 c.71.1.0 (B:1-162) automated matches {Anthrax bacillus (Bacillus anthracis) [TaxId: 1392]}
mivsfmvamdenrvigkdnnlpwrlpselqyvkkttmghplimgrknyeaigrplpgrrn
iivtrnegyhvegcevahsveevfelckneeeififggaqiydlflpyvdklyitkihha
fegdtffpemdmtnwkevfvekgltdeknpytyyyhvyekqq

Timeline for d4elbb1:

• d4elbb1 first appeared in SCOPe 2.02, called d4elbb_
  
• d4elbb1 appears in SCOPe 2.07