SCOP 1.67: Domain d1fm6u_: 1fm6 U:

Lineage for d1fm6u_ (1fm6 U:)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (27 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (10 PDB entries)

8. Domain d1fm6u_: 1fm6 U: [19278]
   Other proteins in same PDB: d1fm6d_, d1fm6x_
   complexed with brl, rea

Details for d1fm6u_

PDB Entry: 1fm6, 2.1 Å

PDB Description: the 2.1 angstrom resolution crystal structure of the heterodimer of the human rxralpha and ppargamma ligand binding domains respectively bound with 9-cis retinoic acid and rosiglitazone and co-activator peptides.

SCOP Domain Sequences for d1fm6u_:

Sequence; same for both SEQRES and ATOM records:

>d1fm6u_ a.123.1.1 (U:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens)}
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Timeline for d1fm6u_:

• d1fm6u_ first appeared (with stable ids) in SCOP 1.55
  
• d1fm6u_ appears in SCOP 1.65
  
• d1fm6u_ appears in SCOP 1.69
  
• d1fm6u_ appears in the current release, SCOPe 2.08