SCOPe 2.08: Domain d4j0sa1: 4j0s A:44-168

Lineage for d4j0sa1 (4j0s A:44-168)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d4j0sa1: 4j0s A:44-168 [192633]
   Other proteins in same PDB: d4j0sa2
   automated match to d3u5la_
   complexed with 1h3, edo

Details for d4j0sa1

PDB Entry: 4j0s, 1.84 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4j0sa1:

Sequence; same for both SEQRES and ATOM records:

>d4j0sa1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

Timeline for d4j0sa1:

• d4j0sa1 first appeared in SCOPe 2.02, called d4j0sa_
  
• d4j0sa1 appears in SCOPe 2.07