SCOPe 2.04: Domain d4hbxa_: 4hbx A:

Lineage for d4hbxa_ (4hbx A:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (182 PDB entries)

8. Domain d4hbxa_: 4hbx A: [192524]
   automated match to d3u5la_
   complexed with 14x

Details for d4hbxa_

PDB Entry: 4hbx, 1.62 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hbxa_:

Sequence; same for both SEQRES and ATOM records:

>d4hbxa_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d4hbxa_:

• d4hbxa_ first appeared in SCOPe 2.02
  
• d4hbxa_ appears in SCOPe 2.03
  
• d4hbxa_ appears in SCOPe 2.05
  
• d4hbxa_ appears in the current release, SCOPe 2.08