SCOPe 2.06: Domain d4a4va_: 4a4v A:

Lineage for d4a4va_ (4a4v A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (173 PDB entries)

8. Domain d4a4va_: 4a4v A: [192492]
   automated match to d3ty0a_
   complexed with yfd

Details for d4a4va_

PDB Entry: 4a4v, 2 Å

PDB Description: Ligand binding domain of human PPAR gamma in complex with amorfrutin 2

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4a4va_:

Sequence, based on SEQRES records:

>d4a4va_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d4a4va_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
skevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlasl
mnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviil
sgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqll
qvikktetdmslhpllqeiykdly

Timeline for d4a4va_:

• d4a4va_ first appeared in SCOPe 2.02
  
• d4a4va_ appears in SCOPe 2.05
  
• d4a4va_ appears in SCOPe 2.07
  
• d4a4va_ appears in the current release, SCOPe 2.08