Lineage for d3v7tc_ (3v7t C:)

  1. Root: SCOPe 2.02
  2. 1103260Class b: All beta proteins [48724] (174 folds)
  3. 1127558Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 1127559Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 1127765Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)
  6. 1127877Protein beta-Tryptase [50546] (1 species)
    ring-like tetramer with active sites facing a central pore
  7. 1127878Species Human (Homo sapiens) [TaxId:9606] [50547] (13 PDB entries)
  8. 1127893Domain d3v7tc_: 3v7t C: [192196]
    automated match to d1a0la_
    complexed with 0gx, co3

Details for d3v7tc_

PDB Entry: 3v7t (more details), 2.09 Å

PDB Description: crystal structure of human beta-tryptase complexed with a synthetic inhibitor with a tropanylamide scaffold
PDB Compounds: (C:) TPSB2 protein

SCOPe Domain Sequences for d3v7tc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3v7tc_ b.47.1.2 (C:) beta-Tryptase {Human (Homo sapiens) [TaxId: 9606]}
ivggqeaprskwpwqvslrvhgpywmhfcggslihpqwvltaahcvgpdvkdlaalrvql
reqhlyyqdqllpvsriivhpqfytaqigadialleleepvkvsshvhtvtlppasetfp
pgmpcwvtgwgdvdnderlpppfplkqvkvpimenhicdakyhlgaytgddvrivrddml
cagntrrdscqgdsggplvckvngtwlqagvvswgegcaqpnrpgiytrvtyyldwihhy
vp

SCOPe Domain Coordinates for d3v7tc_:

Click to download the PDB-style file with coordinates for d3v7tc_.
(The format of our PDB-style files is described here.)

Timeline for d3v7tc_: