SCOPe 2.07: Domain d1dvpa1: 1dvp A:1-145

Lineage for d1dvpa1 (1dvp A:1-145)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.9: ENTH/VHS domain [48464] (5 families)

5. Family a.118.9.2: VHS domain [48468] (6 proteins)

6. Protein Hrs [48469] (1 species)
   protein involved in membrane trafficking and signal transduction

7. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [48470] (1 PDB entry)

8. Domain d1dvpa1: 1dvp A:1-145 [19216]
   Other proteins in same PDB: d1dvpa2
   complexed with cit, zn

Details for d1dvpa1

PDB Entry: 1dvp, 2 Å

PDB Description: crystal structure of the vhs and fyve tandem domains of hrs, a protein involved in membrane trafficking and signal transduction

PDB Compounds: (A:) hepatocyte growth factor-regulated tyrosine kinase substrate

SCOPe Domain Sequences for d1dvpa1:

Sequence; same for both SEQRES and ATOM records:

>d1dvpa1 a.118.9.2 (A:1-145) Hrs {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}
mfrssfcknlenatshlrlepdwpsillicdeinqkdvtpknafaaikkkmnspnphssc
ysllvlesivkncgapvheevftkencemfssflestphenvrqkmlelvqtwayafrss
dkyqaikdtmtilkakghtfpelre

Timeline for d1dvpa1:

• d1dvpa1 first appeared (with stable ids) in SCOP 1.55
  
• d1dvpa1 appears in SCOPe 2.06
  
• d1dvpa1 appears in the current release, SCOPe 2.08