SCOPe 2.05: Domain d3tohb_: 3toh B:

Lineage for d3tohb_ (3toh B:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 (bru isolate) [TaxId:11686] [194276] (20 PDB entries)

8. Domain d3tohb_: 3toh B: [192158]
   automated match to d1sdta_
   complexed with 079, dms

Details for d3tohb_

PDB Entry: 3toh, 1.12 Å

PDB Description: hiv-1 protease - epoxydic inhibitor complex (ph 9 - orthorombic crystal form p212121)

PDB Compounds: (B:) Gag-Pol polyprotein

SCOPe Domain Sequences for d3tohb_:

Sequence; same for both SEQRES and ATOM records:

>d3tohb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 (bru isolate) [TaxId: 11686]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlltqigatlnf

Timeline for d3tohb_:

• d3tohb_ first appeared in SCOPe 2.02
  
• d3tohb_ appears in SCOPe 2.04
  
• d3tohb_ appears in SCOPe 2.06
  
• d3tohb_ appears in the current release, SCOPe 2.08