Lineage for d3s85d_ (3s85 D:)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1320913Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 1320914Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 1320915Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 1320931Protein Human immunodeficiency virus type 1 protease [50632] (8 species)
  7. 1321128Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (421 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 1321963Domain d3s85d_: 3s85 D: [192021]
    automated match to d1izha_
    complexed with lk0

Details for d3s85d_

PDB Entry: 3s85 (more details), 2.8 Å

PDB Description: Discovery of New HIV Protease Inhibitors with Potential for Convenient Dosing and Reduced Side Effects: A-790742 and A-792611.
PDB Compounds: (D:) Protease/Reverse transcriptase

SCOPe Domain Sequences for d3s85d_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3s85d_ b.50.1.1 (D:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

SCOPe Domain Coordinates for d3s85d_:

Click to download the PDB-style file with coordinates for d3s85d_.
(The format of our PDB-style files is described here.)

Timeline for d3s85d_: