SCOPe 2.05: Domain d3qrsb_: 3qrs B:

Lineage for d3qrsb_ (3qrs B:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus type 1 (bru isolate) [TaxId:11686] [194276] (20 PDB entries)

8. Domain d3qrsb_: 3qrs B: [191952]
   automated match to d1mrwa_
   complexed with cl, nk8; mutant

Details for d3qrsb_

PDB Entry: 3qrs, 1.59 Å

PDB Description: HIV-1 protease (mutant Q7K L33I L63I) in complex with a three-armed pyrrolidine-based inhibitor

PDB Compounds: (B:) Protease

SCOPe Domain Sequences for d3qrsb_:

Sequence; same for both SEQRES and ATOM records:

>d3qrsb_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 (bru isolate) [TaxId: 11686]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d3qrsb_:

• d3qrsb_ first appeared in SCOPe 2.02
  
• d3qrsb_ appears in SCOPe 2.04
  
• d3qrsb_ appears in SCOPe 2.06
  
• d3qrsb_ appears in the current release, SCOPe 2.08