SCOPe 2.05: Domain d3o99b_: 3o99 B:

Lineage for d3o99b_ (3o99 B:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (8 species)

7. Species Human immunodeficiency virus 1 [TaxId:11676] [224867] (48 PDB entries)

8. Domain d3o99b_: 3o99 B: [191906]
   automated match to d2f3ka_
   complexed with act, k13, po4

Details for d3o99b_

PDB Entry: 3o99, 1.95 Å

PDB Description: Crystal Structure of wild-type HIV-1 Protease in complex with kd13

PDB Compounds: (B:) Pol polyprotein

SCOPe Domain Sequences for d3o99b_:

Sequence; same for both SEQRES and ATOM records:

>d3o99b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus 1 [TaxId: 11676]}
pqitlwkrplvtiriggqlkealldtgaddtvleemnlpgkwkpkmiggiggfikvrqyd
qipieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d3o99b_:

• d3o99b_ first appeared in SCOPe 2.02
  
• d3o99b_ appears in SCOPe 2.04
  
• d3o99b_ appears in SCOPe 2.06
  
• d3o99b_ appears in the current release, SCOPe 2.08