Lineage for d3o0ua_ (3o0u A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154605Protein (Pro)cathepsin K [54028] (2 species)
  7. 2154606Species Human (Homo sapiens) [TaxId:9606] [54029] (48 PDB entries)
    Uniprot P43235 116-329 ! Uniprot P43235 115-329
  8. 2154611Domain d3o0ua_: 3o0u A: [191903]
    automated match to d2r6na1
    complexed with o47

Details for d3o0ua_

PDB Entry: 3o0u (more details), 1.8 Å

PDB Description: Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG
PDB Compounds: (A:) cathepsin k

SCOPe Domain Sequences for d3o0ua_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3o0ua_ d.3.1.1 (A:) (Pro)cathepsin K {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3o0ua_:

Click to download the PDB-style file with coordinates for d3o0ua_.
(The format of our PDB-style files is described here.)

Timeline for d3o0ua_: