Lineage for d3hptd_ (3hpt D:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056152Protein Coagulation factor Xa, protease domain [50574] (2 species)
  7. 2056155Species Human (Homo sapiens) [TaxId:9606] [50575] (57 PDB entries)
    Uniprot P00742 235-467
  8. 2056165Domain d3hptd_: 3hpt D: [191883]
    Other proteins in same PDB: d3hpta1, d3hpta2, d3hptb_, d3hptc1, d3hptc2
    automated match to d1c5md_
    complexed with act, ca, dms, gol, mes, na, yet

Details for d3hptd_

PDB Entry: 3hpt (more details), 2.19 Å

PDB Description: crystal structure of human fxa in complex with (s)-2-cyano-1-(2- methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl) azepan-3-yl)guanidine
PDB Compounds: (D:) coagulation factor x

SCOPe Domain Sequences for d3hptd_:

Sequence, based on SEQRES records: (download)

>d3hptd_ b.47.1.2 (D:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglp

Sequence, based on observed residues (ATOM records): (download)

>d3hptd_ b.47.1.2 (D:) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthegrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedac
qgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglp

SCOPe Domain Coordinates for d3hptd_:

Click to download the PDB-style file with coordinates for d3hptd_.
(The format of our PDB-style files is described here.)

Timeline for d3hptd_: