SCOPe 2.05: Domain d3b1ma_: 3b1m A:

Lineage for d3b1ma_ (3b1m A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (94 PDB entries)
   Uniprot P37231 232-505

8. Domain d3b1ma_: 3b1m A: [191859]
   automated match to d3prga_
   complexed with krc

Details for d3b1ma_

PDB Entry: 3b1m, 1.6 Å

PDB Description: Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Cerco-A

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3b1ma_:

Sequence, based on SEQRES records:

>d3b1ma_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfk
hitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhei
iytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdla
ifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqi
vtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d3b1ma_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
pesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykdly

Timeline for d3b1ma_:

• d3b1ma_ first appeared in SCOPe 2.02
  
• d3b1ma_ appears in SCOPe 2.04
  
• d3b1ma_ appears in SCOPe 2.06
  
• d3b1ma_ appears in the current release, SCOPe 2.08