SCOPe 2.07: Domain d2yfea_: 2yfe A:

Lineage for d2yfea_ (2yfe A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d2yfea_: 2yfe A: [191837]
   automated match to d3ty0a_
   complexed with yfe

Details for d2yfea_

PDB Entry: 2yfe, 2 Å

PDB Description: Ligand binding domain of human PPAR gamma in complex with amorfrutin 1

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d2yfea_:

Sequence, based on SEQRES records:

>d2yfea_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d2yfea_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
iskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlas
lmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiavii
lsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvql
lqvikktetdmslhpllqeiykdl

Timeline for d2yfea_:

• d2yfea_ first appeared in SCOPe 2.02
  
• d2yfea_ appears in SCOPe 2.06
  
• d2yfea_ appears in the current release, SCOPe 2.08