Lineage for d1e8za1 (1e8z A:525-725)

  1. Root: SCOP 1.61
  2. 148221Class a: All alpha proteins [46456] (151 folds)
  3. 155820Fold a.118: alpha-alpha superhelix [48370] (16 superfamilies)
  4. 155821Superfamily a.118.1: ARM repeat [48371] (10 families) (S)
  5. 155906Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    this is a repeat family; one repeat unit is 1e8y A:598-635 found in domain
  6. 155907Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 155908Species Human (Homo sapiens) [TaxId:9606] [48402] (3 PDB entries)
  8. 155910Domain d1e8za1: 1e8z A:525-725 [19153]
    Other proteins in same PDB: d1e8za2, d1e8za3, d1e8za4

Details for d1e8za1

PDB Entry: 1e8z (more details), 2.4 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine

SCOP Domain Sequences for d1e8za1:

Sequence, based on SEQRES records: (download)

>d1e8za1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens)}
hpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslk
hpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraia
vqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseia
qsrhyqqrfavileaylrgcg

Sequence, based on observed residues (ATOM records): (download)

>d1e8za1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens)}
hpiaraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwg
qqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhy
llqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavilea
ylrgcg

SCOP Domain Coordinates for d1e8za1:

Click to download the PDB-style file with coordinates for d1e8za1.
(The format of our PDB-style files is described here.)

Timeline for d1e8za1: