Lineage for d1e8wa1 (1e8w A:525-725)

  1. Root: SCOP 1.57
  2. 43951Class a: All alpha proteins [46456] (144 folds)
  3. 50498Fold a.118: alpha-alpha superhelix [48370] (11 superfamilies)
  4. 50499Superfamily a.118.1: ARM repeat [48371] (9 families) (S)
  5. 50577Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    this is a repeat family; one repeat unit is 1e8y A:598-635 found in domain
  6. 50578Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 50583Species Pig (Sus scrofa) [TaxId:9823] [48401] (5 PDB entries)
  8. 50588Domain d1e8wa1: 1e8w A:525-725 [19151]
    Other proteins in same PDB: d1e8wa2, d1e8wa3, d1e8wa4

Details for d1e8wa1

PDB Entry: 1e8w (more details), 2.5 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine

SCOP Domain Sequences for d1e8wa1:

Sequence, based on SEQRES records: (download)

>d1e8wa1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Pig (Sus scrofa)}
hpialpkhrptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslk
dpkaypklfssvkwgqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraia
vqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseia
qsrhyqqrfavileaylrgcg

Sequence, based on observed residues (ATOM records): (download)

>d1e8wa1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Pig (Sus scrofa)}
hpialpkhempnqlrkqleaiiatdplnpltaedkellwhfryeslkdpkaypklfssvk
wgqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvl
hyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavil
eaylrgcg

SCOP Domain Coordinates for d1e8wa1:

Click to download the PDB-style file with coordinates for d1e8wa1.
(The format of our PDB-style files is described here.)

Timeline for d1e8wa1: