Lineage for d1e7va1 (1e7v A:525-725)

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 542684Fold a.118: alpha-alpha superhelix [48370] (20 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 542685Superfamily a.118.1: ARM repeat [48371] (17 families) (S)
  5. 542785Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
  6. 542786Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 542791Species Pig (Sus scrofa) [TaxId:9823] [48401] (5 PDB entries)
  8. 542793Domain d1e7va1: 1e7v A:525-725 [19149]
    Other proteins in same PDB: d1e7va2, d1e7va3, d1e7va4
    complexed with ly2; mutant

Details for d1e7va1

PDB Entry: 1e7v (more details), 2.4 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine
PDB Compounds: (A:)

SCOP Domain Sequences for d1e7va1:

Sequence, based on SEQRES records: (download)

>d1e7va1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Pig (Sus scrofa)}
hpialpkhrptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslk
dpkaypklfssvkwgqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraia
vqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseia
qsrhyqqrfavileaylrgcg

Sequence, based on observed residues (ATOM records): (download)

>d1e7va1 a.118.1.6 (A:525-725) Phoshoinositide 3-kinase (PI3K) helical domain {Pig (Sus scrofa)}
hpialpkempnqlrkqleaiiatdplnpltaedkellwhfryeslkdpkaypklfssvkw
gqqeivaktyqllakrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlh
yllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavile
aylrgcg

SCOP Domain Coordinates for d1e7va1:

Click to download the PDB-style file with coordinates for d1e7va1.
(The format of our PDB-style files is described here.)

Timeline for d1e7va1: