SCOPe 2.04: Domain d1rgpa_: 1rgp A:

Lineage for d1rgpa_ (1rgp A:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.116: GTPase activation domain, GAP [48349] (1 superfamily)
   multihelical

4. Superfamily a.116.1: GTPase activation domain, GAP [48350] (3 families)

5. Family a.116.1.1: BCR-homology GTPase activation domain (BH-domain) [48351] (5 proteins)
   Pfam PF00620

6. Protein p50 RhoGAP domain [48352] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48353] (4 PDB entries)

8. Domain d1rgpa_: 1rgp A: [19099]

Details for d1rgpa_

PDB Entry: 1rgp, 2 Å

PDB Description: gtpase-activation domain from rhogap

PDB Compounds: (A:) rhogap

SCOPe Domain Sequences for d1rgpa_:

Sequence, based on SEQRES records:

>d1rgpa_ a.116.1.1 (A:) p50 RhoGAP domain {Human (Homo sapiens) [TaxId: 9606]}
prpplpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvre
vqqkynmglpvdfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpa
tlqvlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlka
inpintftkflldhqgelf

Sequence, based on observed residues (ATOM records):

>d1rgpa_ a.116.1.1 (A:) p50 RhoGAP domain {Human (Homo sapiens) [TaxId: 9606]}
prpplpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvre
vqqkynmglpvdfdqynelhlpavilktflrelpeplltfdlyphvvgflnidesqrvpa
tlqvlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwinpintftkf
lldhqgelf

Timeline for d1rgpa_:

• d1rgpa_ first appeared (with stable ids) in SCOP 1.55, called d1rgp__
  
• d1rgpa_ appears in SCOPe 2.03
  
• d1rgpa_ appears in SCOPe 2.05
  
• d1rgpa_ appears in the current release, SCOPe 2.08