Lineage for Protein: automated matches

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. Family c.77.1.2: Monomeric isocitrate dehydrogenase [82526] (2 proteins)
    the active site is contained within one subunit between the canonical ICDH fold and a large insert domain that itself is a probable rudiment form of ICDH fold resulted from duplication, domain swapping and deletion
    automatically mapped to Pfam PF03971
  6. Protein automated matches [190493] (6 species)
    not a true protein


  1. Acinetobacter baumannii [TaxId:470] [365215] (1 PDB entry)
  2. Corynebacterium glutamicum [TaxId:1718] [187435] (1 PDB entry)
  3. Corynebacterium glutamicum [TaxId:196627] [189781] (1 PDB entry)
  4. Mycobacterium smegmatis [TaxId:1772] [319123] (1 PDB entry)
  5. Mycobacterium tuberculosis [TaxId:83332] [336802] (1 PDB entry)
  6. Pseudomonas aeruginosa [TaxId:287] [355639] (1 PDB entry)

More info for Protein automated matches from c.77.1.2: Monomeric isocitrate dehydrogenase

Timeline for Protein automated matches from c.77.1.2: Monomeric isocitrate dehydrogenase: