SCOPe 2.02: Protein: automated matches

Lineage for Protein: automated matches

Root: SCOPe 2.02
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families)

there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules

Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 proteins)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module

Protein automated matches [190098] (3 species)
not a true protein

Species:

Bacillus stearothermophilus [TaxId:1422] [188729] (3 PDB entries)
1. Domains for 3duf:
  1. Domain d3dufa_: 3duf A: [174232]
    automated match to d1w85a_
    complexed with k, mg, r1t
  2. Domain d3dufc_: 3duf C: [174233]
    automated match to d1w85a_
    complexed with k, mg, r1t
  3. Domain d3dufe_: 3duf E: [174234]
    automated match to d1w85a_
    complexed with k, mg, r1t
  4. Domain d3dufg_: 3duf G: [174235]
    automated match to d1w85a_
    complexed with k, mg, r1t
2. Domains for 3dv0:
  1. Domain d3dv0a_: 3dv0 A: [174255]
    automated match to d1w85a_
    complexed with k, mg, pyr, tpw
  2. Domain d3dv0c_: 3dv0 C: [174256]
    automated match to d1w85a_
    complexed with k, mg, pyr, tpw
  3. Domain d3dv0e_: 3dv0 E: [174257]
    automated match to d1w85a_
    complexed with k, mg, pyr, tpw
  4. Domain d3dv0g_: 3dv0 G: [174258]
    automated match to d1w85a_
    complexed with k, mg, pyr, tpw
3. Domains for 3dva:
  1. Domain d3dvaa_: 3dva A: [174271]
    automated match to d1w85a_
    complexed with k, mg, tpw
  2. Domain d3dvac_: 3dva C: [174272]
    automated match to d1w85a_
    complexed with k, mg, tpw
  3. Domain d3dvae_: 3dva E: [174273]
    automated match to d1w85a_
    complexed with k, mg, tpw
  4. Domain d3dvag_: 3dva G: [174274]
    automated match to d1w85a_
    complexed with k, mg, tpw
Human (Homo sapiens) [TaxId:9606] [186820] (5 PDB entries)
1. Domain for 1wci:
  - Domain d1wcia_: 1wci A: [120890]
    Other proteins in same PDB: d1wcib1, d1wcib2
    automated match to d1olxa_
    complexed with cl, gol, k, mn, wwf
2. Domain for 2beu:
  - Domain d2beua_: 2beu A: [128389]
    Other proteins in same PDB: d2beub1, d2beub2
    automated match to d1olxa_
    complexed with cl, gol, k, mn, so4, thv
3. Domain for 2bev:
  - Domain d2beva_: 2bev A: [128392]
    Other proteins in same PDB: d2bevb1, d2bevb2
    automated match to d1olxa_
    complexed with cl, gol, k, mn, thy
4. Domain for 2bew:
  - Domain d2bewa_: 2bew A: [128395]
    Other proteins in same PDB: d2bewb1, d2bewb2
    automated match to d1olxa_
    complexed with cl, gol, k, mn, thw
5. Domains for 2j9f:
  1. Domain d2j9fa_: 2j9f A: [165952]
    automated match to d1olxa_
    complexed with gol, k, mn, thv
  2. Domain d2j9fc_: 2j9f C: [165953]
    automated match to d1olxa_
    complexed with gol, k, mn, thv
Pseudomonas putida [TaxId:303] [186989] (1 PDB entry)
- Domains for 2bp7:
  1. Domain d2bp7a_: 2bp7 A: [128926]
    Other proteins in same PDB: d2bp7b1, d2bp7b2, d2bp7d1, d2bp7d2, d2bp7f1, d2bp7f2, d2bp7h1, d2bp7h2
    automated match to d1qs0a_
  2. Domain d2bp7c_: 2bp7 C: [128929]
    Other proteins in same PDB: d2bp7b1, d2bp7b2, d2bp7d1, d2bp7d2, d2bp7f1, d2bp7f2, d2bp7h1, d2bp7h2
    automated match to d1qs0a_
  3. Domain d2bp7e_: 2bp7 E: [128932]
    Other proteins in same PDB: d2bp7b1, d2bp7b2, d2bp7d1, d2bp7d2, d2bp7f1, d2bp7f2, d2bp7h1, d2bp7h2
    automated match to d1qs0a_
  4. Domain d2bp7g_: 2bp7 G: [128935]
    Other proteins in same PDB: d2bp7b1, d2bp7b2, d2bp7d1, d2bp7d2, d2bp7f1, d2bp7f2, d2bp7h1, d2bp7h2
    automated match to d1qs0a_

More info for Protein automated matches from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module

Timeline for Protein automated matches from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module:

Protein automated matches from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module first appeared in SCOPe 2.01
Protein automated matches from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module appears in SCOPe 2.03
Protein automated matches from c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module appears in the current release, SCOPe 2.08