Lineage for Protein: automated matches

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2513202Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2513203Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2513204Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
    the active site is between the two identical subunits
  6. 2513401Protein automated matches [190072] (22 species)
    not a true protein

Species:

  1. 2513402Acidithiobacillus thiooxidans [TaxId:930] [187607] (1 PDB entry)
  2. 2513407Archaeoglobus fulgidus [TaxId:2234] [187335] (1 PDB entry)
  3. 2513410Bacillus coagulans [TaxId:1398] [186792] (2 PDB entries)
    1. Domains for 1v53:
      1. 2513411Domain d1v53a_: 1v53 A: [119836]
        automated match to d2ayqb_
      2. 2513412Domain d1v53b_: 1v53 B: [119837]
        automated match to d2ayqb_
    2. Domains for 1v5b:
      1. 2513413Domain d1v5ba_: 1v5b A: [161828]
        automated match to d2ayqb_
        complexed with so4; mutant
      2. 2513414Domain d1v5bb_: 1v5b B: [161829]
        automated match to d2ayqb_
        complexed with so4; mutant
      3. 2513415Domain d1v5bc_: 1v5b C: [161830]
        automated match to d2ayqb_
        complexed with so4; mutant
      4. 2513416Domain d1v5bd_: 1v5b D: [161831]
        automated match to d2ayqb_
        complexed with so4; mutant
      5. 2513417Domain d1v5be_: 1v5b E: [161832]
        automated match to d2ayqb_
        complexed with so4; mutant
      6. 2513418Domain d1v5bf_: 1v5b F: [161833]
        automated match to d2ayqb_
        complexed with so4; mutant
      7. 2513419Domain d1v5bg_: 1v5b G: [161834]
        automated match to d2ayqb_
        complexed with so4; mutant
      8. 2513420Domain d1v5bh_: 1v5b H: [161835]
        automated match to d2ayqb_
        complexed with so4; mutant
  4. 2513421Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [225478] (4 PDB entries)
    1. Domains for 2qfv:
      1. 2513434Domain d2qfva_: 2qfv A: [205785]
        automated match to d4hcxb_
        complexed with nap
      2. 2513435Domain d2qfvb_: 2qfv B: [205786]
        automated match to d4hcxb_
        complexed with nap
      3. 2513436Domain d2qfvc_: 2qfv C: [205787]
        automated match to d4hcxb_
        complexed with nap
      4. 2513437Domain d2qfvd_: 2qfv D: [205788]
        automated match to d4hcxb_
        complexed with nap
    2. Domains for 2qfw:
      1. 2513428Domain d2qfwa_: 2qfw A: [205789]
        automated match to d4hcxb_
        complexed with ict
      2. 2513429Domain d2qfwb_: 2qfw B: [205790]
        automated match to d4hcxb_
        complexed with ict
      3. 2513430Domain d2qfwc_: 2qfw C: [205791]
        automated match to d4hcxb_
        complexed with ict
      4. 2513431Domain d2qfwd_: 2qfw D: [205792]
        automated match to d4hcxb_
        complexed with ict
      5. 2513432Domain d2qfwe_: 2qfw E: [205793]
        automated match to d4hcxb_
        complexed with ict
      6. 2513433Domain d2qfwf_: 2qfw F: [205794]
        automated match to d4hcxb_
        complexed with ict
    3. Domains for 2qfx:
      1. 2513438Domain d2qfxa_: 2qfx A: [205795]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
      2. 2513439Domain d2qfxb_: 2qfx B: [205796]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
      3. 2513440Domain d2qfxc_: 2qfx C: [205797]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
      4. 2513441Domain d2qfxd_: 2qfx D: [205798]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
      5. 2513442Domain d2qfxe_: 2qfx E: [205799]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
      6. 2513443Domain d2qfxf_: 2qfx F: [205800]
        automated match to d4hcxb_
        complexed with akg, ca, ndp
    4. Domains for 2qfy:
      1. 2513422Domain d2qfya_: 2qfy A: [205801]
        automated match to d4hcxb_
        complexed with akg
      2. 2513423Domain d2qfyb_: 2qfy B: [205802]
        automated match to d4hcxb_
        complexed with akg
      3. 2513424Domain d2qfyc_: 2qfy C: [205803]
        automated match to d4hcxb_
        complexed with akg
      4. 2513425Domain d2qfyd_: 2qfy D: [205804]
        automated match to d4hcxb_
        complexed with akg
      5. 2513426Domain d2qfye_: 2qfy E: [205805]
        automated match to d4hcxb_
        complexed with akg
      6. 2513427Domain d2qfyf_: 2qfy F: [205806]
        automated match to d4hcxb_
        complexed with akg
  5. 2513444Burkholderia pseudomallei [TaxId:28450] [188497] (1 PDB entry)
  6. 2513446Burkholderia thailandensis [TaxId:271848] [193254] (1 PDB entry)
  7. 2513449Campylobacter jejuni [TaxId:197] [189804] (2 PDB entries)
    1. Domain for 3udo:
    2. Domains for 3udu:
      1. 2513450Domain d3udua_: 3udu A: [186239]
        automated match to d1cm7a_
        complexed with cl, edo
      2. 2513451Domain d3udub_: 3udu B: [186240]
        automated match to d1cm7a_
        complexed with cl, edo
      3. 2513452Domain d3uduc_: 3udu C: [186241]
        automated match to d1cm7a_
        complexed with cl, edo
      4. 2513453Domain d3udud_: 3udu D: [186242]
        automated match to d1cm7a_
        complexed with cl, edo
      5. 2513454Domain d3udue_: 3udu E: [186243]
        automated match to d1cm7a_
        complexed with cl, edo
      6. 2513455Domain d3uduf_: 3udu F: [186244]
        automated match to d1cm7a_
        complexed with cl, edo
      7. 2513456Domain d3udug_: 3udu G: [186245]
        automated match to d1cm7a_
        complexed with cl, edo
      8. 2513457Domain d3uduh_: 3udu H: [186246]
        automated match to d1cm7a_
        complexed with cl, edo
  8. 2513459Escherichia coli K-12 [TaxId:83333] [189313] (1 PDB entry)
  9. 2513462Escherichia coli [TaxId:562] [193425] (5 PDB entries)
    1. Domain for 4aja:
    2. Domain for 4ajb:
    3. Domain for 4ajc:
    4. Domain for 4ajr:
    5. Domain for 4ajs:
  10. 2513468Escherichia coli [TaxId:833333] [194427] (1 PDB entry)
  11. 2513470Haemophilus influenzae [TaxId:71421] [381589] (1 PDB entry)
  12. 2513473Human (Homo sapiens) [TaxId:9606] [189131] (10 PDB entries)
    1. Domains for 4ja8:
      1. 2513477Domain d4ja8a1: 4ja8 A:41-452 [202723]
        Other proteins in same PDB: d4ja8a2
        automated match to d4ja8b_
        complexed with 1k9, ca, gol, ndp; mutant
      2. 2513478Domain d4ja8b_: 4ja8 B: [197105]
        Other proteins in same PDB: d4ja8a2
        automated match to d1lwda_
        complexed with 1k9, ca, gol, ndp; mutant
    2. Domains for 4umx:
      1. 2513479Domain d4umxa_: 4umx A: [261171]
        automated match to d4l03c_
        complexed with gol, nap, vvs
      2. 2513480Domain d4umxb_: 4umx B: [261172]
        automated match to d4l03c_
        complexed with gol, nap, vvs
    3. Domains for 4umy:
      1. 2513487Domain d4umya_: 4umy A: [261300]
        automated match to d4l03c_
        complexed with gol, nap, so4
      2. 2513488Domain d4umyb_: 4umy B: [263962]
        automated match to d4l03c_
        complexed with gol, nap, so4
    4. Domain for 5i95:
    5. Domains for 5i96:
      1. 2513475Domain d5i96a1: 5i96 A:41-452 [330648]
        Other proteins in same PDB: d5i96a2
        automated match to d1lwda_
        complexed with 69q, act, ca, gol, na, ndp; mutant
      2. 2513476Domain d5i96b_: 5i96 B: [330742]
        Other proteins in same PDB: d5i96a2
        automated match to d1lwda_
        complexed with 69q, act, ca, gol, na, ndp; mutant
    6. Domains for 5svn:
      1. 2513489Domain d5svna_: 5svn A: [329526]
        automated match to d1lwda_
        complexed with ndp, peg; mutant
      2. 2513490Domain d5svnb_: 5svn B: [329529]
        automated match to d1lwda_
        complexed with ndp, peg; mutant
    7. Domains for 5svo:
      1. 2513481Domain d5svoa_: 5svo A: [329523]
        automated match to d1lwda_
        complexed with epe, nap; mutant
      2. 2513482Domain d5svob_: 5svo B: [329580]
        automated match to d1lwda_
        complexed with epe, nap; mutant
    8. Domains for 6adg:
      1. 2513491Domain d6adga_: 6adg A: [357082]
        automated match to d1t0la_
        complexed with 9uo, mg, ndp
      2. 2513492Domain d6adgb_: 6adg B: [356985]
        automated match to d1t0la_
        complexed with 9uo, mg, ndp
      3. 2513493Domain d6adgc_: 6adg C: [356984]
        automated match to d1t0la_
        complexed with 9uo, mg, ndp
    9. Domains for 6adi:
      1. 2513483Domain d6adia1: 6adi A:41-452 [357027]
        Other proteins in same PDB: d6adia2
        automated match to d1lwda_
        complexed with 9uo, ndp
      2. 2513484Domain d6adib_: 6adi B: [357113]
        Other proteins in same PDB: d6adia2
        automated match to d1lwda_
        complexed with 9uo, ndp
    10. Domains for 6vfz:
      1. 2513485Domain d6vfza1: 6vfz A:41-452 [380275]
        Other proteins in same PDB: d6vfza2
        automated match to d1lwda_
        complexed with 9uo, ca, na, ndp; mutant
      2. 2513486Domain d6vfzb_: 6vfz B: [380256]
        Other proteins in same PDB: d6vfza2
        automated match to d1lwda_
        complexed with 9uo, ca, na, ndp; mutant
  13. 2513494Mouse (Mus musculus) [TaxId:10090] [187557] (5 PDB entries)
    1. Domains for 2cmj:
      1. 2513499Domain d2cmja_: 2cmj A: [163446]
        automated match to d1t09a_
        complexed with nap
      2. 2513500Domain d2cmjb_: 2cmj B: [163447]
        automated match to d1t09a_
        complexed with nap
    2. Domains for 2cmv:
      1. 2513495Domain d2cmva_: 2cmv A: [163454]
        automated match to d1t09a_
        complexed with cd, flc, nap
      2. 2513496Domain d2cmvb_: 2cmv B: [163455]
        automated match to d1t09a_
        complexed with cd, flc, nap
    3. Domains for 5h3e:
      1. 2513501Domain d5h3ea_: 5h3e A: [338503]
        automated match to d1lwda_
        complexed with ict, mg; mutant
      2. 2513502Domain d5h3eb_: 5h3e B: [338485]
        automated match to d1lwda_
        complexed with ict, mg; mutant
    4. Domains for 5yzh:
      1. 2513497Domain d5yzha_: 5yzh A: [354389]
        automated match to d1t0la_
        complexed with gol, nap
      2. 2513498Domain d5yzhb_: 5yzh B: [354414]
        automated match to d1t0la_
        complexed with gol, nap
    5. Domains for 5yzi:
      1. 2513503Domain d5yzia_: 5yzi A: [354407]
        automated match to d1t0la_
        complexed with cd, nap
      2. 2513504Domain d5yzib_: 5yzi B: [354392]
        automated match to d1t0la_
        complexed with cd, nap
  14. 2513505Mycobacterium tuberculosis [TaxId:1773] [193947] (1 PDB entry)
  15. 2513508Shewanella oneidensis [TaxId:211586] [194175] (12 PDB entries)
    1. Domain for 3vkz:
    2. Domain for 3vl2:
    3. Domain for 3vl3:
    4. Domain for 3vl4:
    5. Domain for 3vl6:
    6. Domain for 3vl7:
    7. Domain for 3vmj:
    8. Domain for 3vml:
    9. Domain for 3wzv:
    10. Domain for 3wzw:
    11. Domain for 3wzx:
    12. Domain for 3wzy:
  16. 2513521Sinorhizobium meliloti [TaxId:266834] [226269] (1 PDB entry)
  17. 2513524Sulfolobus acidocaldarius [TaxId:330779] [311781] (1 PDB entry)
  18. 2513527Thale cress (Arabidopsis thaliana) [TaxId:3702] [256054] (2 PDB entries)
    1. Domains for 3r8w:
      1. 2513528Domain d3r8wa_: 3r8w A: [249067]
        automated match to d3u1ha_
        complexed with act
      2. 2513529Domain d3r8wb_: 3r8w B: [249068]
        automated match to d3u1ha_
        complexed with act
      3. 2513530Domain d3r8wc_: 3r8w C: [249069]
        automated match to d3u1ha_
        complexed with act
      4. 2513531Domain d3r8wd_: 3r8w D: [249070]
        automated match to d3u1ha_
        complexed with act
    2. Domains for 5j34:
      1. 2513532Domain d5j34a_: 5j34 A: [317267]
        automated match to d3u1hb_
        complexed with mg, so4; mutant
      2. 2513533Domain d5j34b_: 5j34 B: [317263]
        automated match to d3u1hb_
        complexed with mg, so4; mutant
      3. 2513534Domain d5j34c_: 5j34 C: [317313]
        automated match to d3u1hb_
        complexed with mg, so4; mutant
      4. 2513535Domain d5j34d_: 5j34 D: [317363]
        automated match to d3u1hb_
        complexed with mg, so4; mutant
  19. 2513536Thermus thermophilus HB8 [TaxId:300852] [192453] (1 PDB entry)
  20. 2513541Thermus thermophilus [TaxId:274] [189081] (6 PDB entries)
    1. Domain for 2y3z:
    2. Domains for 2y40:
      1. 2513551Domain d2y40a1: 2y40 A:1-345 [170581]
        Other proteins in same PDB: d2y40a2, d2y40b2
        automated match to d1g2ua_
        complexed with mn
      2. 2513552Domain d2y40b1: 2y40 B:1-345 [170582]
        Other proteins in same PDB: d2y40a2, d2y40b2
        automated match to d1g2ua_
        complexed with mn
    3. Domains for 2y41:
      1. 2513543Domain d2y41a1: 2y41 A:1-345 [170583]
        Other proteins in same PDB: d2y41a2, d2y41a3, d2y41b2, d2y41b3
        automated match to d1g2ua_
        complexed with ipm, mn
      2. 2513544Domain d2y41b1: 2y41 B:1-345 [170584]
        Other proteins in same PDB: d2y41a2, d2y41a3, d2y41b2, d2y41b3
        automated match to d1g2ua_
        complexed with ipm, mn
    4. Domains for 2y42:
      1. 2513547Domain d2y42a1: 2y42 A:1-345 [170585]
        Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3
        automated match to d1g2ua_
        complexed with bcn, mn, nad
      2. 2513548Domain d2y42b1: 2y42 B:1-345 [170586]
        Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3
        automated match to d1g2ua_
        complexed with bcn, mn, nad
      3. 2513549Domain d2y42c1: 2y42 C:1-345 [170587]
        Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3
        automated match to d1g2ua_
        complexed with bcn, mn, nad
      4. 2513550Domain d2y42d1: 2y42 D:1-345 [170588]
        Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3
        automated match to d1g2ua_
        complexed with bcn, mn, nad
    5. Domain for 2ztw:
    6. Domains for 4wuo:
      1. 2513545Domain d4wuoa1: 4wuo A:1-345 [261027]
        Other proteins in same PDB: d4wuoa2, d4wuoa3
        automated match to d2y3za_
        complexed with eoh, gol, ipm, k, mn, nad; mutant
      2. 2513546Domain d4wuob_: 4wuo B: [261028]
        Other proteins in same PDB: d4wuoa2, d4wuoa3
        automated match to d2y3za_
        complexed with eoh, gol, ipm, k, mn, nad; mutant
  21. 2513554Trypanosoma brucei [TaxId:5702] [373328] (3 PDB entries)
    1. Domains for 6aj8:
      1. 2513555Domain d6aj8a_: 6aj8 A: [373382]
        automated match to d1t0la_
        complexed with akg, ca, nap
      2. 2513556Domain d6aj8b_: 6aj8 B: [373441]
        automated match to d1t0la_
        complexed with akg, ca, nap
    2. Domains for 6aja:
      1. 2513557Domain d6ajaa_: 6aja A: [373330]
        automated match to d1t0la_
        complexed with akg, ca, gol, nap
      2. 2513558Domain d6ajab_: 6aja B: [373446]
        automated match to d1t0la_
        complexed with akg, ca, gol, nap
      3. 2513559Domain d6ajac_: 6aja C: [373331]
        automated match to d1t0la_
        complexed with akg, ca, gol, nap
      4. 2513560Domain d6ajad_: 6aja D: [373332]
        automated match to d1t0la_
        complexed with akg, ca, gol, nap
    3. Domains for 6ajb:
      1. 2513561Domain d6ajba_: 6ajb A: [373386]
        automated match to d1t0la_
        complexed with akg, ca, nad
      2. 2513562Domain d6ajbb_: 6ajb B: [373329]
        automated match to d1t0la_
        complexed with akg, ca, nad
      3. 2513563Domain d6ajbc_: 6ajb C: [373364]
        automated match to d1t0la_
        complexed with akg, ca, nad
      4. 2513564Domain d6ajbd_: 6ajb D: [373383]
        automated match to d1t0la_
        complexed with akg, ca, nad
  22. 2513565Trypanosoma cruzi [TaxId:353153] [373333] (1 PDB entry)

More info for Protein automated matches from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases

Timeline for Protein automated matches from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: