![]() | Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
![]() | Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily) consists of two intertwined (sub)domains related by pseudo dyad; duplication 3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest |
![]() | Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) ![]() the constituent families form similar dimers |
![]() | Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins) the active site is between the two identical subunits |
![]() | Protein automated matches [190072] (22 species) not a true protein |
![]() | Acidithiobacillus thiooxidans [TaxId:930] [187607] (1 PDB entry) |
![]() | Domain d2d4va_: 2d4v A: [163577] automated match to d1isoa_ complexed with flc, nad |
![]() | Domain d2d4vb_: 2d4v B: [163578] automated match to d1isoa_ complexed with flc, nad |
![]() | Domain d2d4vc_: 2d4v C: [163579] automated match to d1isoa_ complexed with flc, nad |
![]() | Domain d2d4vd_: 2d4v D: [163580] automated match to d1isoa_ complexed with flc, nad |
![]() | Archaeoglobus fulgidus [TaxId:2234] [187335] (1 PDB entry) |
![]() | Domain d2iv0a_: 2iv0 A: [165706] automated match to d1ai2a_ complexed with cl, zn |
![]() | Domain d2iv0b_: 2iv0 B: [165707] automated match to d1ai2a_ complexed with cl, zn |
![]() | Bacillus coagulans [TaxId:1398] [186792] (2 PDB entries) |
![]() | Domain d1v53a_: 1v53 A: [119836] automated match to d2ayqb_ |
![]() | Domain d1v53b_: 1v53 B: [119837] automated match to d2ayqb_ |
![]() | Domain d1v5ba_: 1v5b A: [161828] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bb_: 1v5b B: [161829] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bc_: 1v5b C: [161830] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bd_: 1v5b D: [161831] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5be_: 1v5b E: [161832] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bf_: 1v5b F: [161833] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bg_: 1v5b G: [161834] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Domain d1v5bh_: 1v5b H: [161835] automated match to d2ayqb_ complexed with so4; mutant |
![]() | Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [225478] (4 PDB entries) |
![]() | Domain d2qfva_: 2qfv A: [205785] automated match to d4hcxb_ complexed with nap |
![]() | Domain d2qfvb_: 2qfv B: [205786] automated match to d4hcxb_ complexed with nap |
![]() | Domain d2qfvc_: 2qfv C: [205787] automated match to d4hcxb_ complexed with nap |
![]() | Domain d2qfvd_: 2qfv D: [205788] automated match to d4hcxb_ complexed with nap |
![]() | Domain d2qfwa_: 2qfw A: [205789] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfwb_: 2qfw B: [205790] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfwc_: 2qfw C: [205791] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfwd_: 2qfw D: [205792] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfwe_: 2qfw E: [205793] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfwf_: 2qfw F: [205794] automated match to d4hcxb_ complexed with ict |
![]() | Domain d2qfxa_: 2qfx A: [205795] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfxb_: 2qfx B: [205796] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfxc_: 2qfx C: [205797] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfxd_: 2qfx D: [205798] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfxe_: 2qfx E: [205799] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfxf_: 2qfx F: [205800] automated match to d4hcxb_ complexed with akg, ca, ndp |
![]() | Domain d2qfya_: 2qfy A: [205801] automated match to d4hcxb_ complexed with akg |
![]() | Domain d2qfyb_: 2qfy B: [205802] automated match to d4hcxb_ complexed with akg |
![]() | Domain d2qfyc_: 2qfy C: [205803] automated match to d4hcxb_ complexed with akg |
![]() | Domain d2qfyd_: 2qfy D: [205804] automated match to d4hcxb_ complexed with akg |
![]() | Domain d2qfye_: 2qfy E: [205805] automated match to d4hcxb_ complexed with akg |
![]() | Domain d2qfyf_: 2qfy F: [205806] automated match to d4hcxb_ complexed with akg |
![]() | Burkholderia pseudomallei [TaxId:28450] [188497] (1 PDB entry) |
![]() | Domain d3dmsa_: 3dms A: [174063] automated match to d1ai2a_ |
![]() | Burkholderia thailandensis [TaxId:271848] [193254] (1 PDB entry) |
![]() | Domain d4iwha1: 4iwh A:1-355 [202678] Other proteins in same PDB: d4iwha2 automated match to d4iwhb_ complexed with mg |
![]() | Domain d4iwhb_: 4iwh B: [193255] Other proteins in same PDB: d4iwha2 automated match to d1a05a_ complexed with mg |
![]() | Campylobacter jejuni [TaxId:197] [189804] (2 PDB entries) |
![]() | Domain d3udoa_: 3udo A: [186238] automated match to d1cm7a_ complexed with edo, so4 |
![]() | Domain d3udua_: 3udu A: [186239] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3udub_: 3udu B: [186240] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3uduc_: 3udu C: [186241] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3udud_: 3udu D: [186242] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3udue_: 3udu E: [186243] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3uduf_: 3udu F: [186244] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3udug_: 3udu G: [186245] automated match to d1cm7a_ complexed with cl, edo |
![]() | Domain d3uduh_: 3udu H: [186246] automated match to d1cm7a_ complexed with cl, edo |
![]() | Escherichia coli K-12 [TaxId:83333] [189313] (1 PDB entry) |
![]() | Domain d3lcbc_: 3lcb C: [180177] automated match to d1p8fa_ complexed with amp, atp, mg |
![]() | Domain d3lcbd_: 3lcb D: [180178] automated match to d1p8fa_ complexed with amp, atp, mg |
![]() | Escherichia coli [TaxId:562] [193425] (5 PDB entries) |
![]() | Domain d4ajaa_: 4aja A: [194429] automated match to d1pb1a_ complexed with ca, ict, so4, tap |
![]() | Domain d4ajba_: 4ajb A: [218932] automated match to d4ajca_ complexed with ict, mg, so4, tap; mutant |
![]() | Domain d4ajca_: 4ajc A: [193426] automated match to d1pb1a_ complexed with a2p, akg, ca, so4; mutant |
![]() | Domain d4ajra_: 4ajr A: [219005] automated match to d4ajca_ complexed with akg, mg, nap, nmn; mutant |
![]() | Domain d4ajsa_: 4ajs A: [219006] automated match to d4ajca_ complexed with a2p, ict, mg, nmn, so4; mutant |
![]() | Escherichia coli [TaxId:833333] [194427] (1 PDB entry) |
![]() | Domain d4aj3a_: 4aj3 A: [194428] automated match to d1pb1a_ complexed with ca, ict, nap |
![]() | Haemophilus influenzae [TaxId:71421] [381589] (1 PDB entry) |
![]() | Domain d6xxya_: 6xxy A: [381620] automated match to d3udoa_ complexed with mg, nad, o45 |
![]() | Domain d6xxyb_: 6xxy B: [381590] automated match to d3udoa_ complexed with mg, nad, o45 |
![]() | Human (Homo sapiens) [TaxId:9606] [189131] (10 PDB entries) |
![]() | Domain d4ja8a1: 4ja8 A:41-452 [202723] Other proteins in same PDB: d4ja8a2 automated match to d4ja8b_ complexed with 1k9, ca, gol, ndp; mutant |
![]() | Domain d4ja8b_: 4ja8 B: [197105] Other proteins in same PDB: d4ja8a2 automated match to d1lwda_ complexed with 1k9, ca, gol, ndp; mutant |
![]() | Domain d4umxa_: 4umx A: [261171] automated match to d4l03c_ complexed with gol, nap, vvs |
![]() | Domain d4umxb_: 4umx B: [261172] automated match to d4l03c_ complexed with gol, nap, vvs |
![]() | Domain d4umya_: 4umy A: [261300] automated match to d4l03c_ complexed with gol, nap, so4 |
![]() | Domain d4umyb_: 4umy B: [263962] automated match to d4l03c_ complexed with gol, nap, so4 |
![]() | Domain d5i95a1: 5i95 A:41-452 [330347] Other proteins in same PDB: d5i95a2 automated match to d1lwda_ complexed with act, akg, ca, gol, ndp; mutant |
![]() | Domain d5i96a1: 5i96 A:41-452 [330648] Other proteins in same PDB: d5i96a2 automated match to d1lwda_ complexed with 69q, act, ca, gol, na, ndp; mutant |
![]() | Domain d5i96b_: 5i96 B: [330742] Other proteins in same PDB: d5i96a2 automated match to d1lwda_ complexed with 69q, act, ca, gol, na, ndp; mutant |
![]() | Domain d5svna_: 5svn A: [329526] automated match to d1lwda_ complexed with ndp, peg; mutant |
![]() | Domain d5svnb_: 5svn B: [329529] automated match to d1lwda_ complexed with ndp, peg; mutant |
![]() | Domain d5svoa_: 5svo A: [329523] automated match to d1lwda_ complexed with epe, nap; mutant |
![]() | Domain d5svob_: 5svo B: [329580] automated match to d1lwda_ complexed with epe, nap; mutant |
![]() | Domain d6adga_: 6adg A: [357082] automated match to d1t0la_ complexed with 9uo, mg, ndp |
![]() | Domain d6adgb_: 6adg B: [356985] automated match to d1t0la_ complexed with 9uo, mg, ndp |
![]() | Domain d6adgc_: 6adg C: [356984] automated match to d1t0la_ complexed with 9uo, mg, ndp |
![]() | Domain d6adia1: 6adi A:41-452 [357027] Other proteins in same PDB: d6adia2 automated match to d1lwda_ complexed with 9uo, ndp |
![]() | Domain d6adib_: 6adi B: [357113] Other proteins in same PDB: d6adia2 automated match to d1lwda_ complexed with 9uo, ndp |
![]() | Domain d6vfza1: 6vfz A:41-452 [380275] Other proteins in same PDB: d6vfza2 automated match to d1lwda_ complexed with 9uo, ca, na, ndp; mutant |
![]() | Domain d6vfzb_: 6vfz B: [380256] Other proteins in same PDB: d6vfza2 automated match to d1lwda_ complexed with 9uo, ca, na, ndp; mutant |
![]() | Mouse (Mus musculus) [TaxId:10090] [187557] (3 PDB entries) |
![]() | Domain d5h3ea_: 5h3e A: [338503] automated match to d1lwda_ complexed with ict, mg; mutant |
![]() | Domain d5h3eb_: 5h3e B: [338485] automated match to d1lwda_ complexed with ict, mg; mutant |
![]() | Domain d5yzha_: 5yzh A: [354389] automated match to d1t0la_ complexed with gol, nap |
![]() | Domain d5yzhb_: 5yzh B: [354414] automated match to d1t0la_ complexed with gol, nap |
![]() | Domain d5yzia_: 5yzi A: [354407] automated match to d1t0la_ complexed with cd, nap |
![]() | Domain d5yzib_: 5yzi B: [354392] automated match to d1t0la_ complexed with cd, nap |
![]() | Mycobacterium tuberculosis [TaxId:1773] [193947] (1 PDB entry) |
![]() | Domain d4hcxa_: 4hcx A: [202413] automated match to d4hcxb_ complexed with cl, mn, ndp |
![]() | Domain d4hcxb_: 4hcx B: [193948] automated match to d1lwda_ complexed with cl, mn, ndp |
![]() | Shewanella oneidensis [TaxId:211586] [194175] (12 PDB entries) |
![]() | Domain d3vkza1: 3vkz A:2-364 [217907] Other proteins in same PDB: d3vkza2 automated match to d3vl3a_ complexed with ca, cl, ipm |
![]() | Domain d3vl2a1: 3vl2 A:2-364 [217908] Other proteins in same PDB: d3vl2a2 automated match to d3vl3a_ complexed with ca, cl, ipm |
![]() | Domain d3vl3a1: 3vl3 A:2-364 [195909] Other proteins in same PDB: d3vl3a2 automated match to d1cnza_ complexed with ca, cl, ipm |
![]() | Domain d3vl4a1: 3vl4 A:2-364 [217909] Other proteins in same PDB: d3vl4a2 automated match to d3vl3a_ complexed with ca, cl, ipm |
![]() | Domain d3vl6a1: 3vl6 A:2-364 [217910] Other proteins in same PDB: d3vl6a2 automated match to d3vl3a_ complexed with ca, cl, ipm |
![]() | Domain d3vl7a1: 3vl7 A:2-364 [217911] Other proteins in same PDB: d3vl7a2 automated match to d3vl3a_ complexed with ca, cl, ipm |
![]() | Domain d3vmja1: 3vmj A:2-364 [197351] Other proteins in same PDB: d3vmja2 automated match to d1cnza_ complexed with cl, ipm, mg |
![]() | Domain d3vmla1: 3vml A:2-363 [194176] Other proteins in same PDB: d3vmla2 automated match to d1cnza_ complexed with cl, ipm, mg |
![]() | Domain d3wzva1: 3wzv A:2-364 [278180] Other proteins in same PDB: d3wzva2 automated match to d1cnza_ complexed with ipm, mg |
![]() | Domain d3wzwa1: 3wzw A:2-364 [278178] Other proteins in same PDB: d3wzwa2 automated match to d1cnza_ complexed with ipm, mg |
![]() | Domain d3wzxa1: 3wzx A:2-364 [278181] Other proteins in same PDB: d3wzxa2 automated match to d3vmja_ complexed with ipm, mg; mutant |
![]() | Domain d3wzya1: 3wzy A:2-364 [278177] Other proteins in same PDB: d3wzya2 automated match to d3vmja_ complexed with ipm, mg; mutant |
![]() | Sinorhizobium meliloti [TaxId:266834] [226269] (1 PDB entry) |
![]() | Domain d3us8a_: 3us8 A: [217506] automated match to d4ja8b_ complexed with so4 |
![]() | Domain d3us8b_: 3us8 B: [217507] automated match to d4ja8b_ complexed with so4 |
![]() | Sulfolobus acidocaldarius [TaxId:330779] [311781] (1 PDB entry) |
![]() | Domain d4y1pa_: 4y1p A: [311782] automated match to d1wpwa_ complexed with ipm, mg, so4 |
![]() | Domain d4y1pb_: 4y1p B: [311802] automated match to d1wpwa_ complexed with ipm, mg, so4 |
![]() | Thale cress (Arabidopsis thaliana) [TaxId:3702] [256054] (2 PDB entries) |
![]() | Domain d3r8wa_: 3r8w A: [249067] automated match to d3u1ha_ complexed with act |
![]() | Domain d3r8wb_: 3r8w B: [249068] automated match to d3u1ha_ complexed with act |
![]() | Domain d3r8wc_: 3r8w C: [249069] automated match to d3u1ha_ complexed with act |
![]() | Domain d3r8wd_: 3r8w D: [249070] automated match to d3u1ha_ complexed with act |
![]() | Domain d5j34a_: 5j34 A: [317267] automated match to d3u1hb_ complexed with mg, so4; mutant |
![]() | Domain d5j34b_: 5j34 B: [317263] automated match to d3u1hb_ complexed with mg, so4; mutant |
![]() | Domain d5j34c_: 5j34 C: [317313] automated match to d3u1hb_ complexed with mg, so4; mutant |
![]() | Domain d5j34d_: 5j34 D: [317363] automated match to d3u1hb_ complexed with mg, so4; mutant |
![]() | Thermus thermophilus HB8 [TaxId:300852] [192453] (1 PDB entry) |
![]() | Domain d4f7ia1: 4f7i A:1-345 [192421] Other proteins in same PDB: d4f7ia2, d4f7ia3, d4f7ib2, d4f7ib3, d4f7ic2, d4f7ic3, d4f7id2, d4f7id3 automated match to d1xaaa_ complexed with eoh, gol, ipm, k, mn, mpo, nad |
![]() | Domain d4f7ib1: 4f7i B:1-345 [192422] Other proteins in same PDB: d4f7ia2, d4f7ia3, d4f7ib2, d4f7ib3, d4f7ic2, d4f7ic3, d4f7id2, d4f7id3 automated match to d1xaaa_ complexed with eoh, gol, ipm, k, mn, mpo, nad |
![]() | Domain d4f7ic1: 4f7i C:1-345 [192423] Other proteins in same PDB: d4f7ia2, d4f7ia3, d4f7ib2, d4f7ib3, d4f7ic2, d4f7ic3, d4f7id2, d4f7id3 automated match to d1xaaa_ complexed with eoh, gol, ipm, k, mn, mpo, nad |
![]() | Domain d4f7id1: 4f7i D:1-345 [192424] Other proteins in same PDB: d4f7ia2, d4f7ia3, d4f7ib2, d4f7ib3, d4f7ic2, d4f7ic3, d4f7id2, d4f7id3 automated match to d1xaaa_ complexed with eoh, gol, ipm, k, mn, mpo, nad |
![]() | Thermus thermophilus [TaxId:274] [189081] (6 PDB entries) |
![]() | Domain d2y3za1: 2y3z A:1-345 [170580] Other proteins in same PDB: d2y3za2, d2y3za3 automated match to d1g2ua_ complexed with 2pe, gol, trs |
![]() | Domain d2y40a1: 2y40 A:1-345 [170581] Other proteins in same PDB: d2y40a2, d2y40b2 automated match to d1g2ua_ complexed with mn |
![]() | Domain d2y40b1: 2y40 B:1-345 [170582] Other proteins in same PDB: d2y40a2, d2y40b2 automated match to d1g2ua_ complexed with mn |
![]() | Domain d2y42a1: 2y42 A:1-345 [170585] Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3 automated match to d1g2ua_ complexed with bcn, mn, nad |
![]() | Domain d2y42b1: 2y42 B:1-345 [170586] Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3 automated match to d1g2ua_ complexed with bcn, mn, nad |
![]() | Domain d2y42c1: 2y42 C:1-345 [170587] Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3 automated match to d1g2ua_ complexed with bcn, mn, nad |
![]() | Domain d2y42d1: 2y42 D:1-345 [170588] Other proteins in same PDB: d2y42a2, d2y42a3, d2y42b2, d2y42c2, d2y42c3, d2y42d2, d2y42d3 automated match to d1g2ua_ complexed with bcn, mn, nad |
![]() | Domain d2ztwa_: 2ztw A: [171518] automated match to d1g2ua_ complexed with dei, mg, nad |
![]() | Domain d4wuoa1: 4wuo A:1-345 [261027] Other proteins in same PDB: d4wuoa2, d4wuoa3 automated match to d2y3za_ complexed with eoh, gol, ipm, k, mn, nad; mutant |
![]() | Domain d4wuob_: 4wuo B: [261028] Other proteins in same PDB: d4wuoa2, d4wuoa3 automated match to d2y3za_ complexed with eoh, gol, ipm, k, mn, nad; mutant |
![]() | Trypanosoma brucei [TaxId:5702] [373328] (3 PDB entries) |
![]() | Domain d6aj8a_: 6aj8 A: [373382] automated match to d1t0la_ complexed with akg, ca, nap |
![]() | Domain d6aj8b_: 6aj8 B: [373441] automated match to d1t0la_ complexed with akg, ca, nap |
![]() | Domain d6ajaa_: 6aja A: [373330] automated match to d1t0la_ complexed with akg, ca, gol, nap |
![]() | Domain d6ajab_: 6aja B: [373446] automated match to d1t0la_ complexed with akg, ca, gol, nap |
![]() | Domain d6ajac_: 6aja C: [373331] automated match to d1t0la_ complexed with akg, ca, gol, nap |
![]() | Domain d6ajad_: 6aja D: [373332] automated match to d1t0la_ complexed with akg, ca, gol, nap |
![]() | Domain d6ajba_: 6ajb A: [373386] automated match to d1t0la_ complexed with akg, ca, nad |
![]() | Domain d6ajbb_: 6ajb B: [373329] automated match to d1t0la_ complexed with akg, ca, nad |
![]() | Domain d6ajbc_: 6ajb C: [373364] automated match to d1t0la_ complexed with akg, ca, nad |
![]() | Domain d6ajbd_: 6ajb D: [373383] automated match to d1t0la_ complexed with akg, ca, nad |
![]() | Trypanosoma cruzi [TaxId:353153] [373333] (1 PDB entry) |
![]() | Domain d6ajca_: 6ajc A: [373335] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajcb_: 6ajc B: [373336] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajcc_: 6ajc C: [373337] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajcd_: 6ajc D: [373400] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajce_: 6ajc E: [373334] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajcf_: 6ajc F: [373381] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajcg_: 6ajc G: [373426] automated match to d1t0la_ complexed with ca, ict, nap |
![]() | Domain d6ajch_: 6ajc H: [373367] automated match to d1t0la_ complexed with ca, ict, nap |
Timeline for Protein automated matches from c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases: