SCOPe 2.08: Domain d1ea1a_: 1ea1 A:

Lineage for d1ea1a_ (1ea1 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Cytochrome p450 14 alpha-sterol demethylase (cyp51) [48276] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [48277] (5 PDB entries)
   Uniprot P0A512 P77901

8. Domain d1ea1a_: 1ea1 A: [18970]
   complexed with hem, tpf

Details for d1ea1a_

PDB Entry: 1ea1, 2.21 Å

PDB Description: cytochrome p450 14 alpha-sterol demethylase (cyp51) from mycobacterium tuberculosis in complex with fluconazole

PDB Compounds: (A:) cytochrome p450 51-like rv0764c

SCOPe Domain Sequences for d1ea1a_:

Sequence; same for both SEQRES and ATOM records:

>d1ea1a_ a.104.1.1 (A:) Cytochrome p450 14 alpha-sterol demethylase (cyp51) {Mycobacterium tuberculosis [TaxId: 1773]}
avalprvsgghdehghleefrtdpiglmqrvrdecgdvgtfqlagkqvvllsgshaneff
fragdddldqakaypfmtpifgegvvfdasperrkemlhnaalrgeqmkghaatiedqvr
rmiadwgeageidlldffaeltiytssacligkkfrdqldgrfaklyhelergtdplayv
dpylpiesfrrrdearnglvalvadimngrianpptdksdrdmldvliavkaetgtprfs
adeitgmfismmfaghhtssgtaswtlielmrhrdayaavideldelygdgrsvsfhalr
qipqlenvlketlrlhppliilmrvakgefevqghrihegdlvaaspaisnripedfpdp
hdfvparyeqprqedllnrwtwipfgagrhrcvgaafaimqikaifsvllreyefemaqp
pesyrndhskmvvqlaqpacvryrrrt

Timeline for d1ea1a_:

• d1ea1a_ first appeared (with stable ids) in SCOP 1.55
  
• d1ea1a_ appears in SCOPe 2.07