SCOP 1.67: Domain d1fmia_: 1fmi A:

Lineage for d1fmia_ (1fmi A:)

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.102: alpha/alpha toroid [48207] (5 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.2: Seven-hairpin glycosidases [48225] (1 family)

5. Family a.102.2.1: Class I alpha-1;2-mannosidase, catalytic domain [48226] (1 protein)

6. Protein Class I alpha-1;2-mannosidase, catalytic domain [48227] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48229] (3 PDB entries)

8. Domain d1fmia_: 1fmi A: [18846]
   complexed with ca, so4

Details for d1fmia_

PDB Entry: 1fmi, 1.9 Å

PDB Description: crystal structure of human class i alpha1,2-mannosidase

SCOP Domain Sequences for d1fmia_:

Sequence, based on SEQRES records:

>d1fmia_ a.102.2.1 (A:) Class I alpha-1;2-mannosidase, catalytic domain {Human (Homo sapiens)}
aqgpvhlnyrqkgvidvflhawkgyrkfawghdelkpvsrsfsewfglgltlidaldtmw
ilglrkefeearkwvskklhfekdvdvnlfestirilggllsayhlsgdslflrkaedfg
nrlmpafrtpskipysdvnigtgvahpprwtsdstvaevtsiqlefrelsrltgdkkfqe
avekvtqhihglsgkkdglvpmfinthsglfthlgvftlgaradsyyeyllkqwiqggkq
etqlledyveaiegvrthllrhsepskltfvgelahgrfsakmdhlvcflpgtlalgvyh
glpashmelaqelmetcyqmnrqmetglspeivhfnlypqpgrrdvevkpadrhnllrpe
tveslfylyrvtgdrkyqdwgweilqsfsrftrvpsggyssinnvqdpqkpeprdkmesf
flgetlkylfllfsddpnllsldayvfnteahplpiwt

Sequence, based on observed residues (ATOM records):

>d1fmia_ a.102.2.1 (A:) Class I alpha-1;2-mannosidase, catalytic domain {Human (Homo sapiens)}
aqgpvhlnyrqkgvidvflhawkgyrkfawghdelkpvsrsfsewfglgltlidaldtmw
ilglrkefeearkwvskklhfekdvdvnlfestirilggllsayhlsgdslflrkaedfg
nrlmpafrtpskipysdvnigtgvahpprsdstvaevtsiqlefrelsrltgdkkfqeav
ekvtqhihglsgkkdglvpmfinthsglfthlgvftlgaradsyyeyllkqwiqggkqet
qlledyveaiegvrthllrhsepskltfvgelahgrfsakmdhlvcflpgtlalgvyhgl
pashmelaqelmetcyqmnrqmetglspeivhfnlypqpgrrdvevkpadrhnllrpetv
eslfylyrvtgdrkyqdwgweilqsfsrftrvpsggyssinnvqdpqkpeprdkmesffl
getlkylfllfsddpnllsldayvfnteahplpiwt

Timeline for d1fmia_:

• d1fmia_ first appeared (with stable ids) in SCOP 1.55
  
• d1fmia_ appears in SCOP 1.65
  
• d1fmia_ appears in SCOP 1.69
  
• d1fmia_ appears in the current release, SCOPe 2.08, called d1fmia1