SCOP 1.75: Domain d1ddxd1: 1ddx D:3074-3583

Lineage for d1ddxd1 (1ddx D:3074-3583)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (3 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (2 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Mouse (Mus musculus) [TaxId:10090] [48138] (8 PDB entries)

8. Domain d1ddxd1: 1ddx D:3074-3583 [18735]
   Other proteins in same PDB: d1ddxa2, d1ddxb2, d1ddxc2, d1ddxd2
   complexed with bog, nag, pgx

Details for d1ddxd1

PDB Entry: 1ddx, 3 Å

PDB Description: crystal structure of a mixture of arachidonic acid and prostaglandin bound to the cyclooxygenase active site of cox-2: prostaglandin structure

PDB Compounds: (D:) protein (prostaglandin h2 synthase-2)

SCOP Domain Sequences for d1ddxd1:

Sequence; same for both SEQRES and ATOM records:

>d1ddxd1 a.93.1.2 (D:3074-3583) Prostaglandin H2 synthase {Mouse (Mus musculus) [TaxId: 10090]}
fltriklllkptpntvhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynv
hygyksweafsnlsyytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpq
gsnmmfaffaqhfthqffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgkl
kyqviggevypptvkdtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehnrv
cdilkqehpewgdeqlfqtsrliligetikiviedyvqhlsgyhfklkfdpellfnqqfq
yqnriasefntlyhwhpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiag
rvaggrnvpiavqavakasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelk
alysdidvmelypallvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfgg
evgfkiintasiqslicnnvkgcpftsfnvq

Timeline for d1ddxd1:

• d1ddxd1 first appeared (with stable ids) in SCOP 1.55
  
• d1ddxd1 appears in SCOP 1.73
  
• d1ddxd1 appears in SCOPe 2.01
  
• d1ddxd1 appears in the current release, SCOPe 2.08