Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991828Protein automated matches [190141] (2 species)
    not a true protein
  7. 1991829Species Human (Homo sapiens) [TaxId:9606] [187124] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2h24:
  2. Domain(s) for 3bes:
  3. Domain(s) for 3dgc:
    1. 1991832Domain d3dgcl_: 3dgc L: [173922]
      automated match to d1m4ra_
      complexed with act, cl, ium, u1
    2. 1991833Domain d3dgcm_: 3dgc M: [173923]
      automated match to d1m4ra_
      complexed with act, cl, ium, u1
  4. Domain(s) for 3ux9:
    1. 1991834Domain d3ux9a_: 3ux9 A: [195916]
      Other proteins in same PDB: d3ux9b1, d3ux9b2, d3ux9d1, d3ux9d2
      automated match to d1itfa_
    2. 1991835Domain d3ux9c_: 3ux9 C: [195915]
      Other proteins in same PDB: d3ux9b1, d3ux9b2, d3ux9d1, d3ux9d2
      automated match to d1itfa_

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 automated matches

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.3 automated matches: