SCOPe 2.01: Domain d1prha1: 1prh A:74-586

Lineage for d1prha1 (1prh A:74-586)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (2 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (20 PDB entries)
   Uniprot P05979 32-584

8. Domain d1prha1: 1prh A:74-586 [18710]
   Other proteins in same PDB: d1prha2, d1prhb2
   complexed with hem

Details for d1prha1

PDB Entry: 1prh, 3.5 Å

PDB Description: the x-ray crystal structure of the membrane protein prostaglandin h2 synthase-1

PDB Compounds: (A:) prostaglandin h2 synthase-1

SCOPe Domain Sequences for d1prha1:

Sequence; same for both SEQRES and ATOM records:

>d1prha1 a.93.1.2 (A:74-586) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehqrvc
dllkaehptwgdeqlfqtakliligetikivieeyvqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpdpr

Timeline for d1prha1:

• d1prha1 first appeared (with stable ids) in SCOP 1.55
  
• d1prha1 appears in SCOP 1.75
  
• d1prha1 appears in SCOPe 2.02
  
• d1prha1 appears in the current release, SCOPe 2.08