SCOPe 2.05: Domain d1diya1: 1diy A:74-584

Lineage for d1diya1 (1diy A:74-584)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (4 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (3 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Sheep (Ovis aries) [TaxId:9940] [48137] (23 PDB entries)
   Uniprot P05979 32-584

8. Domain d1diya1: 1diy A:74-584 [18706]
   Other proteins in same PDB: d1diya2
   complexed with acd, bog, coh

Details for d1diya1

PDB Entry: 1diy, 3 Å

PDB Description: crystal structure of arachidonic acid bound in the cyclooxygenase active site of pghs-1

PDB Compounds: (A:) prostaglandin h2 synthase-1

SCOPe Domain Sequences for d1diya1:

Sequence; same for both SEQRES and ATOM records:

>d1diya1 a.93.1.2 (A:74-584) Prostaglandin H2 synthase {Sheep (Ovis aries) [TaxId: 9940]}
iwtwlrttlrpspsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptynia
hdyiswesfsnvsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqg
tnlmfaffaqhfthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklk
yqmlngevyppsveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvc
dllkaehptwgdeqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqy
rnriamefnqlyhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagr
igggrnidhhilhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaelee
lygdidalefypglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfgge
vgfnlvktatlkklvclntktcpyvsfhvpd

Timeline for d1diya1:

• d1diya1 first appeared (with stable ids) in SCOP 1.55
  
• d1diya1 appears in SCOPe 2.04
  
• d1diya1 appears in SCOPe 2.06
  
• d1diya1 appears in the current release, SCOPe 2.08