Lineage for Species: Human (Homo sapiens) [TaxId: 9606]
- Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
Family c.36.1.11: Branched-chain alpha-keto acid dehydrogenase PP module [88766] (5 proteins)
parent family to TK and PFOR
heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
Protein automated matches [190098] (3 species)
not a true protein
Species Human (Homo sapiens) [TaxId:9606] [186820] (5 PDB entries)
PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:
- Domain(s) for 1wci:
Domain d1wcia_: 1wci A: [120890]
Other proteins in same PDB: d1wcib1, d1wcib2
automated match to d1olxa_
complexed with cl, gol, k, mn, wwf
- Domain(s) for 2beu:
Domain d2beua_: 2beu A: [128389]
Other proteins in same PDB: d2beub1, d2beub2
automated match to d1olxa_
complexed with cl, gol, k, mn, so4, thv
- Domain(s) for 2bev:
Domain d2beva_: 2bev A: [128392]
Other proteins in same PDB: d2bevb1, d2bevb2
automated match to d1olxa_
complexed with cl, gol, k, mn, thy
- Domain(s) for 2bew:
Domain d2bewa_: 2bew A: [128395]
Other proteins in same PDB: d2bewb1, d2bewb2
automated match to d1olxa_
complexed with cl, gol, k, mn, thw
- Domain(s) for 2j9f:
Domain d2j9fa_: 2j9f A: [165952]
Other proteins in same PDB: d2j9fb1, d2j9fb2, d2j9fb3, d2j9fd1, d2j9fd2, d2j9fd3
automated match to d1olxa_
complexed with gol, k, mn, thv
Domain d2j9fc_: 2j9f C: [165953]
Other proteins in same PDB: d2j9fb1, d2j9fb2, d2j9fb3, d2j9fd1, d2j9fd2, d2j9fd3
automated match to d1olxa_
complexed with gol, k, mn, thv
More info for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 automated matches
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 automated matches:
- Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 automated matches first appeared in SCOPe 2.01
- Species Human (Homo sapiens) [TaxId:9606] from c.36.1.11 automated matches appears in SCOPe 2.07