SCOPe 2.08: Domain d4a7bb_: 4a7b B:

Lineage for d4a7bb_ (4a7b B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Collagenase-3 (MMP-13) [55540] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55541] (47 PDB entries)

8. Domain d4a7bb_: 4a7b B: [186733]
   automated match to d1euba_
   complexed with 3w4, 3w5, ca, gol, hae, na, zn

Details for d4a7bb_

PDB Entry: 4a7b, 2.2 Å

PDB Description: mmp13 in complex with a novel selective non zinc binding inhibitor cmpd22

PDB Compounds: (B:) collagenase 3

SCOPe Domain Sequences for d4a7bb_:

Sequence; same for both SEQRES and ATOM records:

>d4a7bb_ d.92.1.11 (B:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpg

Timeline for d4a7bb_:

• d4a7bb_ first appeared in SCOPe 2.01
  
• d4a7bb_ appears in SCOPe 2.07