SCOPe 2.06: Domain d3zyaa1: 3zya A:1-353

Lineage for d3zyaa1 (3zya A:1-353)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d3zyaa1: 3zya A:1-353 [186658]
   Other proteins in same PDB: d3zyaa2
   automated match to d1a9ua_
   complexed with 2a8

Details for d3zyaa1

PDB Entry: 3zya, 1.9 Å

PDB Description: Human p38 MAP Kinase in Complex with 2-amino-phenylamino- dibenzosuberone

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d3zyaa1:

Sequence, based on SEQRES records:

>d3zyaa1 d.144.1.7 (A:1-353) automated matches {Human (Homo sapiens) [TaxId: 9606]}
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

Sequence, based on observed residues (ATOM records):

>d3zyaa1 d.144.1.7 (A:1-353) automated matches {Human (Homo sapiens) [TaxId: 9606]}
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglatrwyrape
imlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkiss
esarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyh
dpddepvadpydqsfesrdllidewksltydevisfvpppl

Timeline for d3zyaa1:

• d3zyaa1 first appeared in SCOPe 2.01, called d3zyaa_
  
• d3zyaa1 was called d3zyaa_ in SCOPe 2.05
  
• d3zyaa1 appears in SCOPe 2.07
  
• d3zyaa1 appears in the current release, SCOPe 2.08