SCOPe 2.08: Domain d3ztxb_: 3ztx B:

Lineage for d3ztxb_ (3ztx B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species African clawed frog (Xenopus laevis) [TaxId:8355] [187456] (11 PDB entries)

8. Domain d3ztxb_: 3ztx B: [186571]
   automated match to d1ol5a_
   complexed with ztx

Details for d3ztxb_

PDB Entry: 3ztx, 1.95 Å

PDB Description: Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint sensitivity screen.

PDB Compounds: (B:) serine/threonine-protein kinase 12-a

SCOPe Domain Sequences for d3ztxb_:

Sequence, based on SEQRES records:

>d3ztxb_ d.144.1.7 (B:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvy

Sequence, based on observed residues (ATOM records):

>d3ztxb_ d.144.1.7 (B:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
talaempkrkftiddfdigrplgnvylarekqnkfimalkvlfksqlekegvehqlrrei
eiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeelad
alhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemie
gkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdlisk
llryhppqrlplkgvmehpwvkansrrvlppvy

Timeline for d3ztxb_:

• d3ztxb_ first appeared in SCOPe 2.01
  
• d3ztxb_ appears in SCOPe 2.07