SCOPe 2.01: Domain d3ztxa_: 3ztx A:

Lineage for d3ztxa_ (3ztx A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species African clawed frog (Xenopus laevis) [TaxId:8355] [187456] (6 PDB entries)

8. Domain d3ztxa_: 3ztx A: [186570]
   automated match to d1ol5a_
   complexed with ztx

Details for d3ztxa_

PDB Entry: 3ztx, 1.95 Å

PDB Description: Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint sensitivity screen.

PDB Compounds: (A:) serine/threonine-protein kinase 12-a

SCOPe Domain Sequences for d3ztxa_:

Sequence; same for both SEQRES and ATOM records:

>d3ztxa_ d.144.1.7 (A:) automated matches {African clawed frog (Xenopus laevis) [TaxId: 8355]}
kftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehqlrreieiqs
hlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeeladalhy
cherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemiegkth
dekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdliskllry
hppqrlplkgvmehpwvkansrrvlppvyq

Timeline for d3ztxa_:

• d3ztxa_ is new in SCOPe 2.01-stable
  
• d3ztxa_ appears in SCOPe 2.02
  
• d3ztxa_ appears in the current release, SCOPe 2.08