Lineage for d3zrkb_ (3zrk B:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2219622Protein Glycogen synthase kinase-3 beta (Gsk3b) [69823] (1 species)
    CMGC group; GSK3 subfamily; serine/threonine kinase
  7. 2219623Species Human (Homo sapiens) [TaxId:9606] [69824] (43 PDB entries)
    Uniprot P49841 35-383 ! Uniprot P49841 35-384
  8. 2219643Domain d3zrkb_: 3zrk B: [186534]
    automated match to d1j1bb_
    complexed with gol, so4, zrk

Details for d3zrkb_

PDB Entry: 3zrk (more details), 2.37 Å

PDB Description: Identification of 2-(4-pyridyl)thienopyridinones as GSK-3beta inhibitors
PDB Compounds: (B:) Glycogen synthase kinase-3 beta

SCOPe Domain Sequences for d3zrkb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3zrkb_ d.144.1.7 (B:) Glycogen synthase kinase-3 beta (Gsk3b) {Human (Homo sapiens) [TaxId: 9606]}
kvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfkn
relqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlpv
iyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvs
yicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgt
ptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleac
ahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari

SCOPe Domain Coordinates for d3zrkb_:

Click to download the PDB-style file with coordinates for d3zrkb_.
(The format of our PDB-style files is described here.)

Timeline for d3zrkb_: