Lineage for d3v6sb_ (3v6s B:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218343Protein c-jun N-terminal kinase (jnk3s) [56137] (1 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2218344Species Human (Homo sapiens) [TaxId:9606] [56138] (42 PDB entries)
  8. 2218384Domain d3v6sb_: 3v6s B: [186463]
    automated match to d1jnka_
    complexed with 0f0

Details for d3v6sb_

PDB Entry: 3v6s (more details), 2.97 Å

PDB Description: Discovery of potent and selective covalent inhibitors of JNK
PDB Compounds: (B:) Mitogen-activated protein kinase 10

SCOPe Domain Sequences for d3v6sb_:

Sequence, based on SEQRES records: (download)

>d3v6sb_ d.144.1.7 (B:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyv
vtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcp
efmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidp
akrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmns

Sequence, based on observed residues (ATOM records): (download)

>d3v6sb_ d.144.1.7 (B:) c-jun N-terminal kinase (jnk3s) {Human (Homo sapiens) [TaxId: 9606]}
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglavtryyrapevilg
mgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrny
venrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhp
yinvwydpaeveapppqiqlderehtieewkeliykevmns

SCOPe Domain Coordinates for d3v6sb_:

Click to download the PDB-style file with coordinates for d3v6sb_.
(The format of our PDB-style files is described here.)

Timeline for d3v6sb_: