Lineage for d3uxha_ (3uxh A:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1837702Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. 1838447Superfamily c.23.5: Flavoproteins [52218] (9 families) (S)
  5. 1838601Family c.23.5.3: Quinone reductase [52235] (4 proteins)
    binds FAD
  6. 1838657Protein Quinone reductase type 2 (menadione reductase) [52240] (1 species)
  7. 1838658Species Human (Homo sapiens) [TaxId:9606] [52241] (53 PDB entries)
  8. 1838669Domain d3uxha_: 3uxh A: [186430]
    automated match to d1qr2a_
    complexed with fad, uxh, zn

Details for d3uxha_

PDB Entry: 3uxh (more details), 1.53 Å

PDB Description: design, synthesis and biological evaluation of potetent quinoline and pyrroloquinoline ammosamide analogues as inhibitors of quinone reductase 2
PDB Compounds: (A:) Ribosyldihydronicotinamide dehydrogenase [quinone]

SCOPe Domain Sequences for d3uxha_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3uxha_ c.23.5.3 (A:) Quinone reductase type 2 (menadione reductase) {Human (Homo sapiens) [TaxId: 9606]}
agkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtls
npevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvl
cqgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcg
fkvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

SCOPe Domain Coordinates for d3uxha_:

Click to download the PDB-style file with coordinates for d3uxha_.
(The format of our PDB-style files is described here.)

Timeline for d3uxha_: