SCOPe 2.01: Domain d3up2a_: 3up2 A:

Lineage for d3up2a_ (3up2 A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d3up2a_: 3up2 A: [186368]
   automated match to d1ol5a_
   complexed with 0c8, edo

Details for d3up2a_

PDB Entry: 3up2, 2.3 Å

PDB Description: Aurora A in complex with RPM1686

PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d3up2a_:

Sequence; same for both SEQRES and ATOM records:

>d3up2a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreve
iqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelana
lsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrdtlcgtldylppemieg
rmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrl
lkhnpsqrpmlrevlehpwitanssk

Timeline for d3up2a_:

• d3up2a_ is new in SCOPe 2.01-stable
  
• d3up2a_ appears in SCOPe 2.02
  
• d3up2a_ appears in the current release, SCOPe 2.08