SCOPe 2.05: Domain d3tjdb_: 3tjd B:

Lineage for d3tjdb_ (3tjd B:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d3tjdb_: 3tjd B: [185860]
   automated match to d1u46a_
   complexed with 6tp

Details for d3tjdb_

PDB Entry: 3tjd, 2.9 Å

PDB Description: co-crystal structure of Jak2 with thienopyridine 19

PDB Compounds: (B:) Tyrosine-protein kinase JAK2

SCOPe Domain Sequences for d3tjdb_:

Sequence, based on SEQRES records:

>d3tjdb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptqfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdferei
eilkslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikllqytsq
ickgmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespif
wyapeslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhli
ellknngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnmag

Sequence, based on observed residues (ATOM records):

>d3tjdb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dptqfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdferei
eilkslqhdnivkykgvcysnlklimeylpygslrdylqkhkeridhikllqytsqickg
meylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwyap
eslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliellk
nngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnmag

Timeline for d3tjdb_:

• d3tjdb_ first appeared in SCOPe 2.01
  
• d3tjdb_ appears in SCOPe 2.04
  
• d3tjdb_ appears in SCOPe 2.06
  
• d3tjdb_ appears in the current release, SCOPe 2.08