SCOPe 2.07: Domain d3sxra1: 3sxr A:411-671

Lineage for d3sxra1 (3sxr A:411-671)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (892 PDB entries)

8. Domain d3sxra1: 3sxr A:411-671 [185577]
   Other proteins in same PDB: d3sxra2, d3sxrb2
   automated match to d1k2pa_
   complexed with 1n1, so4

Details for d3sxra1

PDB Entry: 3sxr, 2.4 Å

PDB Description: Crystal structure of BMX non-receptor tyrosine kinase complex with dasatinib

PDB Compounds: (A:) Cytoplasmic tyrosine-protein kinase BMX

SCOPe Domain Sequences for d3sxra1:

Sequence, based on SEQRES records:

>d3sxra1 d.144.1.7 (A:411-671) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkreeitllkelgsgqfgvvklgkwkgqydvavkmikegsmsedeffqeaqtmmklshp
klvkfygvcskeypiyivteyisngcllnylrshgkglepsqllemcydvcegmaflesh
qfihrdlaarnclvdrdlcvkvsdfgmtryvlddqyvssvgtkfpvkwsapevfhyfkys
sksdvwafgilmwevfslgkmpydlytnsevvlkvsqghrlyrphlasdtiyqimyscwh
elpekrptfqqllssieplre

Sequence, based on observed residues (ATOM records):

>d3sxra1 d.144.1.7 (A:411-671) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkreeitllkelgsvvklgkwkgqydvavkmikegsmsedeffqeaqtmmklshpklvk
fygvcskeypiyivteyisngcllnylrshgkglepsqllemcydvcegmafleshqfih
rdlaarnclvdrdlcvkvsdfgmtryvlddqyvssvgtkfpvkwsapevfhyfkyssksd
vwafgilmwevfslgkmpydlytnsevvlkvsqghrlyrphlasdtiyqimyscwhelpe
krptfqqllssieplre

Timeline for d3sxra1:

• d3sxra1 first appeared in SCOPe 2.01, called d3sxra_
  
• d3sxra1 appears in SCOPe 2.06
  
• d3sxra1 appears in the current release, SCOPe 2.08