SCOP 1.75: Domain d1foeg1: 1foe G:1035-1239

Lineage for d1foeg1 (1foe G:1035-1239)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.87: DBL homology domain (DH-domain) [48064] (1 superfamily)
   multihelical; core: 5-helical bundle

4. Superfamily a.87.1: DBL homology domain (DH-domain) [48065] (1 family)

5. Family a.87.1.1: DBL homology domain (DH-domain) [48066] (10 proteins)
   Pfam PF00621

6. Protein GEF of TIAM1 (T-Lymphoma invasion and metastasis inducing protein 1) [48073] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [48074] (1 PDB entry)

8. Domain d1foeg1: 1foe G:1035-1239 [18520]
   Other proteins in same PDB: d1foea2, d1foeb_, d1foec2, d1foed_, d1foee2, d1foef_, d1foeg2, d1foeh_
   complexed with so4; mutant

Details for d1foeg1

PDB Entry: 1foe, 2.8 Å

PDB Description: crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1

PDB Compounds: (G:) t-lymphoma invasion and metastasis inducing protein 1

SCOP Domain Sequences for d1foeg1:

Sequence; same for both SEQRES and ATOM records:

>d1foeg1 a.87.1.1 (G:1035-1239) GEF of TIAM1 (T-Lymphoma invasion and metastasis inducing protein 1) {Mouse (Mus musculus) [TaxId: 10090]}
lsdadklrkvicelletertyvkdlnclmerylkplqketfltqdeldvlfgnltemvef
qveflktledgvrlvpdleklekvdqfkkvlfslggsflyyadrfklysafcashtkvpk
vlvkaktdtafkafldaqnprqqhsstlesylikpiqrvlkyplllrelfaltdaeseeh
yhldvaiktmnkvashinemqkihe

Timeline for d1foeg1:

• d1foeg1 first appeared (with stable ids) in SCOP 1.55
  
• d1foeg1 appears in SCOP 1.73
  
• d1foeg1 appears in SCOPe 2.01
  
• d1foeg1 appears in the current release, SCOPe 2.08