Lineage for d3rlqa1 (3rlq A:9-225)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2579776Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2579777Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2579778Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)
  6. 2579779Protein HSP90 [55876] (3 species)
  7. 2579883Species Human (Homo sapiens) [TaxId:9606] [55878] (146 PDB entries)
    Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223
  8. 2579932Domain d3rlqa1: 3rlq A:9-225 [185026]
    Other proteins in same PDB: d3rlqa2, d3rlqb2
    automated match to d1osfa_
    complexed with 3rq, po4

Details for d3rlqa1

PDB Entry: 3rlq (more details), 1.9 Å

PDB Description: co-crystal structure of the hsp90 atp binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7h-pyrrolo[2,3- d]pyrimidine-5- carbonitrile
PDB Compounds: (A:) Heat shock protein HSP 90-alpha

SCOPe Domain Sequences for d3rlqa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3rlqa1 d.122.1.1 (A:9-225) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
dqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdps
kldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadi
smigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvil
hlkedqteyleerrikeivkkhsqfigypitlfveke

SCOPe Domain Coordinates for d3rlqa1:

Click to download the PDB-style file with coordinates for d3rlqa1.
(The format of our PDB-style files is described here.)

Timeline for d3rlqa1:

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d3rlqa2