Lineage for d3rigb1 (3rig B:34-302)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107522Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 protein domains)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2107583Protein automated matches [191258] (3 species)
    not a true protein
  7. 2107587Species Human (Homo sapiens) [TaxId:9606] [189817] (16 PDB entries)
  8. 2107600Domain d3rigb1: 3rig B:34-302 [184983]
    Other proteins in same PDB: d3riga2, d3rigb2
    automated match to d2b4ya1
    complexed with nhe, zn

Details for d3rigb1

PDB Entry: 3rig (more details), 2 Å

PDB Description: sirt5 is an nad-dependent protein lysine demalonylase and desuccinylase
PDB Compounds: (B:) NAD-dependent deacetylase sirtuin-5

SCOPe Domain Sequences for d3rigb1:

Sequence, based on SEQRES records: (download)

>d3rigb1 c.31.1.5 (B:34-302) automated matches {Human (Homo sapiens) [TaxId: 9606]}
arpsssmadfrkffakakhiviisgagvsaesgvptfrgaggywrkwqaqdlatplafah
npsrvwefyhyrrevmgskepnaghraiaecetrlgkqgrrvvvitqnidelhrkagtkn
lleihgslfktrctscgvvaenykspicpalsgkgapepgtqdasipveklprceeagcg
gllrphvvwfgenldpaileevdrelahcdlclvvgtssvvypaamfapqvaargvpvae
fntettpatnrfrfhfqgpcgttlpeala

Sequence, based on observed residues (ATOM records): (download)

>d3rigb1 c.31.1.5 (B:34-302) automated matches {Human (Homo sapiens) [TaxId: 9606]}
arpsssmadfrkffakakhiviisgaaggywrkwqaqdlatplafahnpsrvwefyhyrr
evmgskepnaghraiaecetrlgkqgrrvvvitqnidelhrkagtknlleihgslfktrc
tscgvvaenykspicpalsgkgapepgtqdasipveklprceeagcggllrphvvwfgen
ldpaileevdrelahcdlclvvgtssvvypaamfapqvaargvpvaefntettpatnrfr
fhfqgpcgttlpeala

SCOPe Domain Coordinates for d3rigb1:

Click to download the PDB-style file with coordinates for d3rigb1.
(The format of our PDB-style files is described here.)

Timeline for d3rigb1:

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Domains from same chain:
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d3rigb2