SCOPe 2.08: Domain d3rcha_: 3rch A:

Lineage for d3rcha_ (3rch A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.6: Pyridoxal-dependent decarboxylase [69565] (4 proteins)
   automatically mapped to Pfam PF00282

6. Protein automated matches [191129] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189764] (2 PDB entries)

8. Domain d3rcha_: 3rch A: [184881]
   automated match to d1js3a_
   complexed with plp

Details for d3rcha_

PDB Entry: 3rch, 2.8 Å

PDB Description: Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the open conformation with LLP and PLP bound to Chain-A and Chain-B respectively

PDB Compounds: (A:) aromatic L-amino acid decarboxylase

SCOPe Domain Sequences for d3rcha_:

Sequence, based on SEQRES records:

>d3rcha_ c.67.1.6 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mnasefrrrgkemvdyvanymegiegrqvypdvepgylrplipaaapqepdtfediindv
ekiimpgvthwhspyffayfptassypamladmlcgaigcigfswaaspacteletvmmd
wlgkmlelpkaflnekagegggviqgsaseatlvallaartkvihrlqaaspeltqaaim
eklvayssdqahssveragliggvklkaipsdgnfamrasalqealerdkaaglipffmv
atlgtttccsfdnllevgpicnkediwlhvdaayagsaficpefrhllngvefadsfnfn
phkwllvnfdcsamwvkkrtdltgafrldptylkhshqdsglitdyrhwqiplgrrfrsl
kmwfvfrmygvkglqayirkhvqlshefeslvrqdprfeicvevilglvcfrlkgsnkvn
eallqrinsakkihlvpchlrdkfvlrfaicsrtvesahvqrawehikelaadvlraere

Sequence, based on observed residues (ATOM records):

>d3rcha_ c.67.1.6 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mnasefrrrgkemvdyvanymegiegrqvypdvepgylrplipaaapqepdtfediindv
ekiimpgvthwhspyffayfptassypamladmlcgaigcispacteletvmmdwlgkml
elpkaflnekagegggviqgsaseatlvallaartkvihrlqaaspeltqaaimeklvay
ssdqahssveragliggvklkaipsdgnfamrasalqealerdkaaglipffmvatlgtt
tccsfdnllevgpicnkediwlhvdaayagsaficpefrhllngvefadsfnfnphkwll
vnfdcsamwvkkrtdltgafrrfrslkmwfvfrmygvkglqayirkhvqlshefeslvrq
dprfeicvevilglvcfrlkgsnkvneallqrinsakkihlvpchlrdkfvlrfaicsrt
vesahvqrawehikelaadvlraere

Timeline for d3rcha_:

• d3rcha_ first appeared in SCOPe 2.01
  
• d3rcha_ appears in SCOPe 2.07